مرور دوره 5, شماره 2 بر اساس تاریخ انتشار

در حال نمایش موارد 1 - 20 از 187

  • P 99: Self-Assembling Peptide Scaffolds as New Therapeutic Method in TBI: Focused on Bioactive Motifs 

    Bayat Tork, Mohammad Amin؛ Saberifar, Mohsen؛ Sahab Nega, Sajjad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Traumatic brain injury (TBI) is a common reason of brain tissue loss as a result of tumors, accidents, and surgeries. Renewal of the brain parenchyma is restricted by many reasons such as inimical substances produced as ...

  • P 69: Effect of Serum Zinc Element in Epilepsy Paitaints 

    Ghane, Zahra؛ Bahrami, Nafise؛ Hassan nia, Malihe؛ Behmanesh, Yasaman (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Epilepsy is a disorder categorized by recurrent seizures and leads to changes in neuronal death and neurogenesis. Recently the search for new targets in the therapy of epilepsy has focused on brain inflammation because ...

  • P 100: Stem Cells as Neuroinflammatory Modulator in TBI: A Narrative Review 

    Saberifar, Mohsen؛ Bayat Tork, Mohammad Amin؛ Sahab Negah, Sajjad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Traumatic brain injury (TBI) is physical damage to the brain structure which has a high global rate of mortality and morbidity. TBI can cause intense inflammatory response due to accumulation of leukocytes in cerebral ...

  • P 2: Proliferation of Neural Stem Cells Promotes in Presence of Feijoa Methanolic Extract in the Oxidative Stress Condition 

    Haratizadeh, Sara؛ Akhtari, Javad؛ Ebrahim Zadeh, Mohammad Ali؛ Abdanipour, Alireza؛ Nazm Bojnordi, Maryam؛ Ghasemi Hamidabadi, Hatef (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Introduction: Now days, several studies have indicated the central nervous system has capacity for endogenous repair. But, the proliferation of endogenous neural stem cells (NSCs) is insufficient for treatment of ...

  • P 82: The Transplantation of Human Umbilical Cord Mesenchymal Stem Cells in Neonatal Strokes 

    Miraghel, Alma؛ Rambod Rad, Niloofar؛ Behrooz nia, Zahra (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Brain injuries that caused by strokes (result of intra partum ischemia) are a frequent cause of prenatal mortality and morbidity with limited therapeutic options. Transplanting human mesenchymal stem cells (hmscs) indicates ...

  • P 108: Evaluation of Calcineurin Role in Neuroinflmmation: Possible Targets for Early Detection and Treatment 

    Ahmadi, Mokhtar؛ Feizi, Hossein؛ Shahbeigi, Fatemeh (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Calcineurin (CaN) is a Ca2+/calmodulin (Ca2+/CaM)-dependent serine/threonine protein phosphatase expressed in most mammalian tissues but found at higher concentration in brain. In the last decade there have been a steadily ...

  • P 147: Role of Sparstolonin B in Intracerebral Hemorrhage-Induced Inflammatory Brain Injury: Blocking the Formation of TLR2/TLR4 Heterodimer 

    Akhgari, Niloufar؛ Kamandi, Neda؛ Sahab Negah, Sajad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Intra-cerebral hemorrhage (ICH) is a particularly severe type of stroke accounting for 10–15 % of all strokes and is associated with a mortality rate of 30–50%. Neuroinflammation contributes to ICH-induced secondary brain ...

  • O 4: Kynurenine Impairs MbMEC Function in Vitro Through Arylhydrocarbon Receptor Activation 

    Epping, Lisa؛ Ruck, Tobias؛ Platten, Michael؛ Loser, Karin؛ Meuth, Sven (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    In the development of neuroinflammatory diseases, alterations of the blood brain barrier (BBB) represent key events. The integrity of the BBB is partially maintained by endothelia cells (ECs), since they actively limit the ...

  • P 90: The Role of miR-146a in Inflammatory Process of Mesial Temporal Lobe Epilepsy (MTLE): Implication for Therapy 

    Banakermani, Sarah؛ Hasanzadeh Kahani, Mohadese (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Epilepsy is the third most common chronic brain disorder which is characterized by an enduring predisposition to generate seizures. Mesial Temporal Lobe Epilepsy (MTLE) is the most common type of refractory epilepsy. ...

  • P 153: Neuroinflammation in Multiple Sclerosis 

    Vakilzadeh, Gelareh (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Multiple sclerosis (MS) is a complex disease which is correlated with increasing inflammatory factors, demyelination and axonal loss. In this auto-immune disease, Neuroinflammation is mediated by different types of T cells ...

  • P 88: Matrix Metalloproteinases in Neuroinflammation 

    Forouzanfar, Fatemeh؛ Khorrami, Mohammad Bagher؛ Sahab Negah, Sajad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important in normal development, cellular differentiation or migration, angiogenesis, neurogenesis, wound repair, and a wide range of pathological ...

  • O 9: Immunomodulatory Effects of Neural Stem Cell on Multiple Sclerosis: A Systematic Review 

    Sheykhian, Sanaz؛ Sahab Negah, Sajad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are chronic inflammatory demyelinating disorders of central nervous system (CNS). While the cause is unclear, the fundamental ...

  • P 76: Assay of Alterations of Cytokines to Remedy of Traumatic Brain Injury 

    Salahshour, Fateme؛ Ghari, Shima (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Traumatic brain injury (TBI) is a global health concern that typically causes emotional disturbances and cognitive dysfunction. It elicits a complex secondary injury response, with neuroinflammation as a crucial central ...

  • P 75: Inflammation in the Pathogenesis of Depression 

    Ghanei Sarcheshmeh, Mohadese (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Depression is a mental disorder that results from changes in the central nervous system (CNS) that may result from immunological abnormalities. According to the World Health Organization, major depression will become the ...

  • P 148: The Role of Cannabinoids in Ischemia Stroke 

    Khorrami, Mohammad Bagher؛ Forouzanfar, Fatemeh؛ Sadeghnia, Hamid R؛ Sahab Negah, Sajad (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Inflammation serves a protective function in controlling infections and promoting tissue repair, and can also cause damage to tissue and disease. Many types of cells involved in this process, expressing the components of ...

  • P 111: Use of Stem Cell Therapy for Treatment of Temporal Lobe Epilepsy (TLE) 

    Arminfar, Samane (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Epilepsy is one of the most common neuroinflammatory disorders that affect more than 50 million people worldwide. Excessive electrical discharges in neurons following neural cell damage or loss leads to recurrent seizures, ...

  • O 21: A Case of Anti-NMDA Receptor Encephalitis Who Presented with Status Epilepticus 

    Farzad-Fard, Mohammad Taghi (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is is most common form ofimmune-mediated encephalitis with prominent neurologic and psychiatric features at disease onset. We describe a 16 years old patient who ...

  • P 112: Combining Granulocyte-Colony Stimulating Factor (G-CSF) and Stem Cells in Treatment of Traumatic Brain Injury (TBI) 

    Mehri, Ali؛ Vakilzadeh, Mohammad Moein؛ Heidari, Amirhossein (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Traumatic brain injury (TBI) is described as a situation in which the brain is damaged by an external force. It is considered to be a chief problem in health care. Pharmacotherapy and stem cell therapy are the main treatments ...

  • P 44: The Role of HCN Channels in T Cell Function 

    Greiff, Johannes؛ Epping, Lisa؛ Ruck, Tobias؛ Leonhardt, Julia؛ Meuth, Sven G (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Ion channels play a major role in the regulation of T cell function in health and disease. In a computer-based model, established to simulate T cells’ membrane potential (VM) generation, we discovered a discrepancy between ...

  • O 20: The Role of Neuroinflammation in Epilepsy: A New Target for Treatment 

    Gorji, Ali؛ Khaleghi Ghadiri, Maryam (تهران مرکز تحقیقات علوم اعصاب شفاء, 2017-04-01)
    Despite progress in pharmacological and surgical treatments of epilepsy, little is known about the processes that a healthy brain is rendered epileptic after seizure occurrence. Growing evidence supports the involvement ...