Expression of estrogenic response genes to different concentration of 17ß-estradiol in male mosquitofish (Gambusia yucatana)

Abstract

The estrogenic effects of endocrine disrupting compounds in fish are not reversible and can reduce populations. Sensitive methods such as Q-PCR, Western blot, etc., have been used to determine changes in gene expression and this predict the effects before they become irreversible. The present study was designed to detect the expression of the estrogen receptors vitellogenin and pregnane X indicates that they are potentially useful molecular markers for detecting the presence of endocrine disrupting compounds in the environ