Is Spinal Anesthesia with Low Dose Lidocaine Better than Sevoflorane Anesthesia in Patients Undergoing Hip Fracture Surgery

Abstract

Background: To evaluate general anesthesia with sevoflurane vs spinal anesthesia with low dose lidocaine 5% on<br />hemodynamics changes in patients undergoing hip fracture surgery.<br />Methods: In this randomized double blind trial 100 patients (50 patients in each group) older than 60 years under<br />hip surgery were randomized in general anesthesia with sevoflurane and spinal anesthesia with lidocaine 5%.<br />Hemodynamic changes including mean arterial pressure (MAP) and heart rate, blood loss, pain severity, nausea and<br />vomiting and opioids consumption were compared in two groups.<br />Results: During surgery, difference between two groups regarding changes in mean arterial pressure was not<br />significant, but the changes in heart rate were significantly different. Mean arterial pressure changes during recovery<br />between two groups were significantly different. But there was no significant difference in heart rate changes. Bleeding<br />in the sevoflurane group was significantly more than spinal group (513.ml vs. 365 ml). Moreover, AS Score, opioid<br />consumption, and the nausea and vomiting in spinal anesthesia group was significantly lower than the sevoflurane<br />group.<br />Conclusion: We showed that general anesthesia with sevoflurane and spinal anesthesia with low dose lidocaine 5%<br />have comparable effects on hemodynamics changes in patients undergoing hip fracture surgery. However postoperative<br />pain score, vomiting and morphine consumption in patients with spinal anesthesia were lower than general anesthesia.