Clinical Outcomes of Total Hip Arthroplasty in Patients with Ankylosed Hip

Abstract

Background: <br/> <br/><span style="font-size: xx-small; font-family: ArialMT;">Various drugs are administered intra-articularly to provide postoperative analgesia after arthroscopic</span> <br/>knee surgery. The purpose of this study was to assess the analgesic effects of intra-articular injection of a dexmedetomidine <br/> <br/>following knee arthroscopy. <br/> <br/> <br/>Methods: <br/> <br/><span style="font-size: xx-small; font-family: ArialMT;">Forty six patients schadualed for arthroscopic knee surgery under general anaesthesia, were randomly</span> <br/>devided into two groups. Intervention group received 1μg/kg dexmedetomidine (D) and isotonic saline. Control group <br/> <br/>received 25ml isotonic saline (P). Analgesic effects were evaluated by measuring pain intensity (VAS scores) and <br/> <br/>duration of analgesia. <br/> <br/> <br/>Results: <br/> <br/><span style="font-size: xx-small; font-family: ArialMT;">There was no significant difference between the two groups in terms of age, sex and weight. The mean of</span> <br/>post-operation pain severity in 1, 3, 6,12, and 24 h was significantly lower in the intervention group (D) in comparison <br/> <br/>with the control group (P). the mean of the total dose of tramadol consumption was significantly lower in the interven <br/> <br/> <br/> <br/><span style="font-size: xx-small; font-family: ArialMT;">tion</span> <br/>group in comparison with the control group ( <br/> <br/> <br/><em><span style="font-size: xx-small; font-family: Arial-ItalicMT;"><em><span style="font-size: xx-small; font-family: Arial-ItalicMT;">P</span></em></span></em> <br/><span style="font-size: xx-small; font-family: ArialMT;"><0.001).</span> <br/> <br/>Conclusions: <br/> <br/><span style="font-size: xx-small; font-family: ArialMT;">Intra-articular injection of dexmedetomidine at the end of arthroscopic knee surgery, alleviates the</span> <br/> <br/>patients' pain; reducing the postoperative need for narcotics as analgesics, and increase the first analgesic request <br/>after operation.