Neonatal Tuberous Sclerosis Complex with Large and Multiple Cardiac Rhabdomyomas

Abstract

The tuberous sclerosis complex (TSC) is most commonly diagnosed around the age of 5 years. Neonatal TSC is rare. The important neonatal manifestations include cardiac rhabdomyomas, central nervous system abnormalities, and skin manifestations. We describe a neonate suffering the TSC with large and multiple cardiac rhabdomyomas. The largest rhabdomyoma measured 3.6 cm × 2 cm almost filling the right ventricle. The neonate did not have any symptoms. She continued to remain asymptomatic until 8 months' follow-up. (Iranian Heart Journal 2016; 17(3):51-54)