Roles of Kermanshahi Oil, Animal Fat, Dietary and Non- ietary Vitamin D and other Nutrients in Increased Risk f Premenopausal Breast Cancer: A Case Control Study in ermanshah, Iran

Abstract

<b>Background:</b> Kermanshahi oil is one the most favorable oils in Iran especially in Kermanshah province. We imed to evaluate the role of usual intake of Kermanshahi oil and other kinds of dietary fats as well as different eats, vegetables and fruits, carbohydrates, cereals, grains, sweets, candy and lifestyle habits in risk of breast ancer. Materials and <br/><b>Methods</b>: A case-control study with 47 consecutive, newly diagnosed premenopausal breastcancer atients and 105 age and socioeconomic matched healthy women was conducted from 2013-2014 in Imam eza hospital of Kermanshah using a standardized, validated questionnaire assessing various anthropometric, cio-demographic, lifestyle and dietary characteristics. <br/><b>Results</b>: Kermanshahi oil intake was associated with a .1-fold (OR= 2.123, 95% CI 1.332- 3.38) (p= 0.002) higher likelihood of having breast cancer, while daily intake f other solid animal fats also increased the likelihood by 2.8-fold (OR = 2.754, 95% CI 1.43- 5.273) (p < 0.001), fter various adjustments made. Lack of fish oil, white meat, vegetables, soy products, nuts and dairy products especially during adolescence) in daily regimens and lack of sun exposure were significantly associated with remenopausal breast cancer risk in this region. <br/><b>Conclusions</b>: This study suggested that animal fat increases he risk of premenopausal breast cancer but many other dietary and non-dietary factors including calcium and itamin D deficiency are consistently associated with increased odds of breast cancer in this region.