Case-Control Study of Diet in Patients with Cervical Cancer or Precancerosis in Wufeng, a High Incidence Region in China

Abstract

Purpose: To investigate the diet of patients with cervical cancer and precancerosis in the Wufeng area, a highincidenceregion in China. <br/><b>Methods</b>: In the case group, 104 patients diagnosed with cervical cancer or cervicalintraepithelial neoplasias (CINⅡ/Ⅲ) were recruited from the Wufeng area. Nine hundred thirty-six healthywomen were selected from the same area as the matched controls. A questionnaire, which included questionsabout general lifestyle conditions, smoking and alcohol status, source of drinking water, green tea intake, anddiet in the past year, was presented to all participants. <br/><b>Results</b>: Green tea intake (P=0.022, OR=0.551, 95%CI=0.330-0.919) and vegetable intake (P=0.035, OR=0.896, 95% CI=0.809-0.993) were identified as protectivefactors against cervical cancer or CINⅡ/Ⅲ. There was no indication of any associations of other lifestyle factors(smoking status, alcohol status, source of drinking water) or diet (intake of fruit, meat/egg/milk, soybean food,onion/garlic, staple food and pickled food) with cervical cancer. <br/><b>Conclusions</b>: The results suggest that eatingmore fresh vegetables and drinking more green tea may help to reduce the risk of cervical cancer or CINⅡ/Ⅲin people of the Wufeng area.