Lack of Efficacy of Tai Chi in Improving Quality of Life in Breast Cancer Survivors: a Systematic Review and Meta-analysis

Abstract

<b>Background:</b> It is controversial whether Tai Chi (TC) benefits breast cancer survivors (BCS) on quality of life(QoL). We therefore undertook a meta-analysis to assess this question. Materials and <br/><b>Methods</b>: A computerizedsearch through electronic databases was performed to identify relevant randomized controlled trials (RCTs). Theprimary outcome was QoL, while secondary outcomes included body mass index (BMI), bone mineral density(BMD), and muscle strength. <br/><b>Results</b>: Five RCTs involving 407 patients were included in the meta-analysis. Thepooled standardized mean differences were 0.10 (95% confidence interval (CI): -0.35-0.54) for physical wellbeing,0.03 (95%CI: -0.18-0.25) for social/family well-being, 0.24 (95%CI: 0.02-0.45) for emotional well-being,0.23 (95%CI: -0.03-0.49) for functional well-being, and 0.09 (95%CI: -0.19-0.36) for additional concerns. TCfailed to improve BMI, BMD, and muscle strength. <br/><b>Conclusions</b>: There is currently lack of sufficient evidenceto support TC improving QoL and other important clinical endpoints.