Prevalence of Human Papillomavirus in Women from Saudi Arabia

Abstract

<b>Background:</b> Human papillomavirus (HPV) infection is the main causes of cervical cancer in womenworldwide. The goal of the present study was to determine the prevalence and distribution of HPV genotypes inwomen from Saudi Arabia. Recently, several HPV detection methods have been developed, each with differentsensitivities and specificities. <br/><b>Methods</b>: In this study, total forty cervical samples were subjected to polymerasechain reaction and hybridization to BioFilmChip microarray assessment. <br/><b>Results</b>: Human papillomavirus(HPV) infections were found in 43% of the specimens. The most prevalent genotypes were HPV 16 (30%) HPV18 (8.0%) followed by type HPV 45, occurring at 5.0%. <br/><b>Conclusion</b>: Our finding showed the HPV infection andprevalence is increasing at alarming rate in women of Saudi Arabia. There was no low risk infection detected inthe tested samples. The BioFilmChip microarray detection system is highly accurate and suitable for detectionof single and multiple infections, allowing rapid detection with less time-consumption and easier performanceas compared with other methods.