Characteristics of Gynecologic Oncology Patients in King Chulalongkorn Memorial Hospital - Complications and Outcome of Pelvic Exenteration

Abstract

<strong>Background:</strong> Pelvic exenteration is a procedure which includes enbloc resection of pelvic organs followed bysurgical reconstruction. Aims include both cure and palliation but data for pelvic exenteration in Thailand arevery limited. <br /><strong>Objective</strong>: This study was conducted to evaluate characteristics of patients, operative procedureoutcomes and complications. Materials and <br /><strong>Methods</strong>: This retrospective review covered all of the charts ofexenteration patients during January 2002 to December 2011. Baseline characteristic of the patients werecollected as well as details of clinical results. <br /><strong>Results</strong>: A total of 13 cases of pelvic exenteration were included.Most underwent total pelvic exenteration (9 cases) and the remainder posterior and anterior exenteration. Theirprimary cancers were ovarian, cervical and vulva. Mean operative time was 532 minutes (SD 160.2, range 270-750) and estimated blood loss was 2830 ml (1850, 1000-8000). Mean tumor size was 7.33 cm (3.75, 4-15). Meanhospital stay was 35.2 days (29.8, 13-109). The most common post operative complication was urinary tractinfection. Overall disease free survival with a negative surgical margin was significantly better than in positivesurgical margin patients (p=0.014). <br /><strong>Conclusions</strong>: Surgical margin was the most significant prognostic factor fordisease free survival, in line with earlier studies.