نمایش مختصر رکورد

dc.contributor.authorSarhadi, Susanen_US
dc.contributor.authorGholizadeh, Mostafaen_US
dc.contributor.authorMoghadasian, Tinaen_US
dc.contributor.authorGolmohamadzadeh, Shivaen_US
dc.date.accessioned1399-07-09T08:22:04Zfa_IR
dc.date.accessioned2020-09-30T08:22:04Z
dc.date.available1399-07-09T08:22:04Zfa_IR
dc.date.available2020-09-30T08:22:04Z
dc.date.issued2020-03-01en_US
dc.date.issued1398-12-11fa_IR
dc.date.submitted2019-04-15en_US
dc.date.submitted1398-01-26fa_IR
dc.identifier.citationSarhadi, Susan, Gholizadeh, Mostafa, Moghadasian, Tina, Golmohamadzadeh, Shiva. (2020). Moisturizing effects of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using deionized and magnetized water by <i>in vivo</i> and <i>in vitro</i> methods. Iranian Journal of Basic Medical Sciences, 23(3), 337-343. doi: 10.22038/ijbms.2020.39587.9397en_US
dc.identifier.issn2008-3866
dc.identifier.issn2008-3874
dc.identifier.urihttps://dx.doi.org/10.22038/ijbms.2020.39587.9397
dc.identifier.urihttp://ijbms.mums.ac.ir/article_14634.html
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/340086
dc.description.abstract<em><strong>Objective(s):</strong></em> The present study aimed to determine and compare moisturizing and occlusion effects of different solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using magnetized water and deionized water.<br /><em><strong>Materials and Methods:</strong></em> SLN formulations were prepared using various lipids, including Tripalmitin, Compritol®, Precirol®, and emulsifiers including Poloxamer and Tween 80. NLC formulations were also prepared with oleic acid and the same solid lipids. Two types of formulations were prepared; first with deionized water and then with magnetized water. Formulations were prepared using high shear homogenization and ultrasound methods. The products were analyzed by PSA (particle size analyzer), DSC (differential scanning calorimetry), and TEM (transmission electron microscopy). The moisturizing effect of formulations was determined by in vivo and in vitro methods. <br /><em><strong>Results:</strong></em> Findings of the assessments demonstrated that in products prepared with magnetized water, 5% SLN Precirol® had the most moisturizing effect in vivo and 5% SLN Compritol® had the most moisturizing effect in vitro. The use of magnetized water in formulations can improve the effectiveness and increase the stability of moisturizing products.<br /><em><strong>Conclusion:</strong></em> In this study, all products prepared with magnetized water showed more stability, smaller size, and more moisturizing effects compared with products prepared with deionized water.en_US
dc.format.extent903
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherMashhad University of Medical Sciencesen_US
dc.relation.ispartofIranian Journal of Basic Medical Sciencesen_US
dc.relation.isversionofhttps://dx.doi.org/10.22038/ijbms.2020.39587.9397
dc.subjectDeionized wateren_US
dc.subjectMagnetized wateren_US
dc.subjectNLCen_US
dc.subjectSkin drynessen_US
dc.subjectSLNen_US
dc.titleMoisturizing effects of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using deionized and magnetized water by <i>in vivo</i> and <i>in vitro</i> methodsen_US
dc.typeTexten_US
dc.typeOriginal Articleen_US
dc.contributor.departmentDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iranen_US
dc.contributor.departmentDepartment of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iranen_US
dc.contributor.departmentDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iranen_US
dc.contributor.departmentNanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iranen_US
dc.citation.volume23
dc.citation.issue3
dc.citation.spage337
dc.citation.epage343
nlai.contributor.orcid0000-0003-4770-5529
nlai.contributor.orcid0000-0002-9947-2248
nlai.contributor.orcid0000-0002-5370-6643


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