مرور Volume 20, Issue 12 بر اساس عنوان
در حال نمایش موارد 1 - 14 از 14
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Anti-hyperglycemic and antioxidant potential of Croton bonplandianus. Bail fractions in correlation with polyphenol content
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s):Diabetes mellitus, a carbohydrate metabolic disorder, occurs due to absolute or relative deficiency of insulin. Current treatment strategies involve either preventing or delaying the ...
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Antimalarial and cytotoxic activities of roots and fruits fractions of Astrodaucus persicus extract
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s):Astrodaucus persicus (Apiaceae) is one of the two species of this genus which grows in different parts of Iran. Roots of this plant were rich in benzodioxoles and used as ...
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Curcumin enhances liver SIRT3 expression in the rat model of cirrhosis
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Bill duct ligation (BDL) is a representative model of biliary cholestasis in animals. Curcumin has a protective effect on the liver; however, its underlying mechanisms are not ...
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Cytotoxic and apoptotic effects of root extract and tanshinones isolated from Perovskia abrotanoides Kar
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s):Perovskia abrotanoides Kar., from family Lamiaceae, is a little known medicinal plant growing in various regions of Iran. In the present study, cryptotanshinone (CT), tanshinone ...
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Effect of fetal and adult bovine serum on pyocyanin production in Pseudomonas aeruginosa isolated from clinical and soil samples
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Pyocyanin is a blue-greenish redox-active pigment, produced by Pseudomonas aeruginosa, with a wide range of biological and biotechnological applications. Pyocyanin biosynthesis ...
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The effects of activated-omental extract on nuclear and cytoplasmic in vitro maturation of rat oocytes
(Mashhad University of Medical Sciences, 2017-12-01)Objective: The role of growth factors, including vascular endothelial growth factor of activated omentum on mitosis is clearly known, though not on all the aspects of in vitro oocyte ...
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The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports. The aim of this study was to confine the ...
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Genistein preserves the lungs of ovariectomized diabetic rats: addition to apoptotic and inflammatory markers in the lung
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): The role of isoflavones in pulmonary structure and function during menopause is not well studied. Moreover, the important role of estrogen in the physiological function of respiratory ...
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Mechanisms of spinal cord injury regeneration in zebrafish: a systematic review
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s):To determine the molecular and cellular mechanisms of spinal cord regeneration in zebrafish. Materials and Methods: Medical databases of PubMed and ...
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Neuroprotection of a sesamin derivative, 1, 2-bis [(3-methoxy- phenyl) methyl] ethane-1, 2-dicaroxylic acid (MMEDA) against ischemic and hypoxic neuronal injury
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Stroke may cause severe neuronal damage. The sesamin have been demonstrated to possess neuroprotection by its antioxidant and anti-inflammatory properties. One sesamin derivative was ...
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The role of sirolimus in proteinuria in diabetic nephropathy rats
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): The aim of this study was to observe the impact of sirolimus on proteinuria in streptozotocin (STZ) induced diabetic rats. Materials and Methods: Rats ...
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Sodium hydrosulfide upregulates mRNA and protein expression of TGF-α in gastric mucosa in experimental model of stimulated gastric acid secretion in rats
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Transforming growth factor alpha (TGF-α) has been shown to modulate the gastric acid secretion. Therefore, the aim of the present study was to investigate the effect of sodium ...
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Vitamin E improved bone strength and bone minerals in male rats given alcohol
(Mashhad University of Medical Sciences, 2017-12-01)Objective(s): Alcohol consumption induces oxidative stress on bone, which in turn increases the risk of osteoporosis. This study determined the effects of vitamin E on bone strength and bone mineral ...



