مرور Volume 19, Issue 10 بر اساس عنوان
در حال نمایش موارد 1 - 12 از 12
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Alkyl cross-linked low molecular weight polypropyleneimine dendrimers as efficient gene delivery vectors
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): First, 10-bromodecanoic acid was covalently attached to all available surface primary amines of PPI G2 and G3 to increase their lipophilicity. In the subsequent step, PPIs were ...
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Anti-hyperglycaemic and antioxidant effects of Bidens tripartita and quantitative analysis on its active principles
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): Bidens species are used for their antidiabetic properties traditionally in many countries. Aim of this study is to evaluate hypoglycaemic and antidiabetic activity of ...
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Biochemical characterization of PE_PGRS61 family protein of Mycobacterium tuberculosis H37Rv reveals the binding ability to fibronectin
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): The periodic binding of protein expressed by Mycobacterium tuberculosis H37Rv with the host cell receptor molecules i.e. fibronectin (Fn) is gaining significance because of ...
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Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s):Long-term treatment with antipsychotics causes serious side effects such as tardive dyskinesia that characterized by abnormal movements in the orofacial region. Oxidative stress in ...
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Development of 153Sm-DTPA-SPION as a theranostic dual contrast agents in SPECT/MRI
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): This study describes the preparation, biodistribution of 153Sm-DTPA-SPION after intravenous injection in rats. Materials and Methods: The chelator ...
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The effect of sugar cane molasses on the immune and male reproductive systems using in vitro and in vivo methods
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): Sugar cane molasses is a commonly used ingredient in several food products. Contrasting reports suggest that molasses may have potential adverse or beneficial effects on human health. ...
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The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid ...
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Effects of sex steroid hormones on neuromedin S and neuromedin U2 receptor expression following experimental traumatic brain injury
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): Neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (TBI). Two of these ...
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Gamma reactivation using the spongy effect of KLF1-binding site sequence: an approach in gene therapy for beta-thalassemia
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): β-thalassemia is one of the most common genetic disorders in the world. As one of the promising treatment strategies, fetal hemoglobin (Hb F) can be induced. The present study was ...
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Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): This study aims to determine the effects of ozone therapy on restoring impaired Nrf2 activation to ameliorate chronic tubulointerstitial injury in rats with ...
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Pharmacokinetic study of furosemide incorporated PLGA microspheres after oral administration to rat
(Mashhad University of Medical Sciences, 2016-10-01)Objective(s): The purpose of the current study was to assess the feasibility of microspheres from biocompatible polymer for oral bioavailability (BA) enhancement of potent sulfonamide- type loop ...
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The role of exosomes contents on genetic and epigenetic alterations of recipient cancer cells
(Mashhad University of Medical Sciences, 2016-10-01)Exosomes, as a mediator of cell-to-cell transfer of genetic information, act an important role in intercommunication between tumor cells and their niche including fibroblasts, endothelial cells, adipocytes and monocytes. ...
