مرور Volume 23, Issue 8 بر اساس عنوان
در حال نمایش موارد 1 - 9 از 9
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Bioinformatics prediction and experimental validation of VH antibody fragment interacting with <i>Neisseria meningitidis</i> factor H binding protein
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): We previously conducted an in silico research on the interactions between the ribosome display-selected single chain variable fragment (scFv) and factor H binding protein (fHbp) of ...
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Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl ...
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Differential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in ...
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The effect of adipose-derived mesenchymal stem cells on renal function and histopathology in a rat model of ischemia-reperfusion induced acute kidney injury
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): It has been shown that adipose-derived mesenchymal stem cells (AD-MSC) have protective effects in acute kidney injury (AKI). This study was conducted to assess the therapeutic effects ...
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Evaluating the effect of arachidonic acid and eicosapentaenoic acid on induction of adipogenesis in human adipose-derived stem cells
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): Adipose tissue is one of the most important endocrine organs that liberates many metabolic mediators such as hormones, cytokines, and chemokines. Different types of fatty acids have ...
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Interaction of perforin and granzyme B and HTLV-1 viral factors is associated with ATL development
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): Human T cell leukaemia virus type 1 (HTLV-1) is associated with adult T cell leukaemia (ATL), a malignant lymphoproliferative disease that infects CD4 T cells. It is not clear why ...
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Left ventricular phosphorylation patterns of Akt and ERK1/2 after triiodothyronine intracoronary perfusion in isolated hearts and short-term <i>in vivo</i> treatment in Wistar rats
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): To determine the effects of triiodothyronine (T3) intracoronary perfusion in isolated hearts and short-term administration in rats on the left ventricular (LV) phosphorylation patterns ...
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Magnesium supplementation enhances insulin sensitivity and decreases insulin resistance in diabetic rats
(Mashhad University of Medical Sciences, 2020-08-01)Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of ...
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Natural and herbal compounds targeting breast cancer, a review based on cancer stem cells
(Mashhad University of Medical Sciences, 2020-08-01)Cancer stem cells (CSCs) are known as the major reason for therapy resistance. Recently, natural herbal compounds are suggested to have a significant role in inhibiting the breast cancer stem cells (BCSCs). The aim of this ...
