مرور Volume 22, Issue 8 بر اساس تاریخ انتشار
در حال نمایش موارد 1 - 11 از 11
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The effect of intra-cerebroventricular injection of insulin on the levels of monoamines on the raphe magnus nucleus of non-diabetic and short-term diabetic rats in the formalin test
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Systemic and intracerebroventricular (ICV) injection of insulin possess analgesic effects. The raphe magnus nucleus (RMN) is part of the endogenous analgesia system. The objective ...
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The efficacy and molecular mechanism of the effect of schisandrin b on the treatment of erectile dysfunction
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): The purpose of this study is to determine the efficacy and molecular mechanism of the effect of schisandrin b (SCHB) on treating erectile dysfunction (ED) in a rat model with bilateral ...
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Prevalence of antibiotic resistance and integrons, <i>sul</i> and <i>Smqnr</i> genes in clinical isolates of <i>Stenotrophomonas maltophilia</i> from a tertiary care hospital in Southwest Iran
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Stenotrophomonas maltophilia has emerged as an important opportunistic nosocomial pathogen due to its intrinsic and acquired resistance to a wide range of antimicrobial agents. The ...
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Effect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): MicroRNAs (miRNAs) could regulate many cellular processes such as proliferation and differentiation. let-7a miRNA is one of the key regulators in the developmental transition of ...
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<i>Pterocarpus santalinus</i> ameliorates streptozotocin-induced diabetes mellitus via anti-inflammatory pathways and enhancement of insulin function
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Morbidity and mortality due to diabetes mellitus (DM) result in exorbitant psycho-economical costs, so there is a strong need to create new strategies and drugs for controlling DM. ...
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The impact of <i>Lactobacillus acidophilus</i> on hepatic and colonic fibrosis induced by ethephon in a rat model
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): The study is aimed to elucidate the impact of antioxidant, anti-inflammatory and antifibrosis properties of Lactobacillus acidophilus (L. acidophilus) on liver and colon in ethephon ...
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Assessment of DNA vaccine encoding <i>Toxoplasma gondii</i> microneme complete gene and IL-12 as adjuvant in BALB/c mice
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Toxoplasma gondii is an obligate intracellular protozoan parasite that causes toxoplasmosis in humans and animals. Micronemes (MICs) are effective candidates for DNA vaccine. ...
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An overview of therapeutic applications of ultrasound based on synergetic effects with gold nanoparticles and laser excitation
(Mashhad University of Medical Sciences, 2019-08-01)Acoustic cavitation which occurs at high intensities of ultrasound waves can be fatal for tumor cells. The existence of dissolved gases and also the presence of nanoparticles (NPs) in a liquid, irradiated by ultrasound, ...
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MiR-96 induced non-small-cell lung cancer progression through competing endogenous RNA network and affecting EGFR signaling pathway
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Non-small cell lung cancer (NSCLC) has become a serious global health problem in the 21st century, and tumor proliferation and metastasis are the leading causes of death in patients ...
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Pharmacological evidence for lithium-induced neuroprotection against methamphetamine-induced neurodegeneration via Akt-1/GSK3 and CREB-BDNF signaling pathways
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Neurodegeneration is an outcome of Methamphetamine (METH) abuse. Studies have emphasized on the neuroprotective properties of lithium. The current study is designed towards evaluating ...
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Pioglitazone abrogates testicular damage induced by testicular torsion/detorsion in rats
(Mashhad University of Medical Sciences, 2019-08-01)Objective(s): Testicular torsion/detorsion (T/D) is a well-known cause for infertility. Pioglitazone is an agonist of peroxisome proliferator activated receptor-gamma (PPAR-γ). Previous studies ...
