Volume 20, Issue 7
مرور بر اساس
ارسال های اخیر
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Umbelliprenin induced both anti-inflammatory and regulatory cytokines in C57/BL6 mice
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Umbelliprenin is a prenyloxy-coumarin with pharmacologically polyvalent activity. Several studies have shown its anti-inflammatory, anti-tumor, antioxidant, and antigenotoxic activity, ...
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Naringin attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress and NF-κB activation in vivo and in vitro
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Naringin, an essential flavonoid, inhibits inflammatory response and oxidative stress in diabetes. However, whether ...
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Effect of chondroitinase ABC on inflammatory and oxidative response following spinal cord injury
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Chondroitinase ABC (cABC) treatment improves functional recovery following spinal cord injury (SCI) through degrading inhibitory molecules to axon growth. However, cABC involvement ...
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Evaluation of phytochemicals, antioxidant and burn wound healing activities of Cucurbita moschata Duchesne fruit peel
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Cucurbita moschata Duchesne (pumpkin) is a well-known plant with several pharmacological effects. The aim of the present study was to assess burn wound healing activity of ...
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The cardioprotective effect of vanillic acid on hemodynamic parameters, malondialdehyde, and infarct size in ischemia-reperfusion isolated rat heart exposed to PM10
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Particulate matter (PM) exposure can promote cardiac ischemia and myocardial damage. The effects of PM10 on hemodynamic parameters, lipid peroxidation, and infarct size ...
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Crocin has anti-inflammatory and protective effects in ischemia-reperfusion induced renal injuries
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Crocus sativus (saffron) has been widely used in traditional medicine. It has also been found to possess many beneficial properties in modern medicine. The most important ...
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Cardiovascular effects of nitrergic system of the pedunculopon-tine tegmental nucleus in anesthetized rats
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Nitric oxide (NO) is an important neurotransmitter in central nervous system involved in central cardiovascular regulation. The presence of NO in the pedunculopontine tegmental (PPT) ...
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Heterologous expression of a truncated form of human recombinant vascular endothelial growth factor-A and its biological activity in wound healing
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Vascular endothelial growth factor (VEGF) is one of the most effective proteins in angiogenesis, mesenchymal stem cells (MSCs) differentiation and wound healing. These abilities are ...
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Expression of pro-inflammatory genes in lesions, spleens and blood neutrophils after burn injuries in mice treated with silver sulfodiazine
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): It is now supposed that cytokines released during the burn injuries have a great impact on the immunological and pathological responses after the burn. The main objective of this ...
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Effect of eugenol on lithium-pilocarpine model of epilepsy: behavioral, histological, and molecular changes
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Epilepsy establishment gives rise to biochemical and morphological changes in the hippocampus. Oxidative stress, morphological changes, and mossy fiber sprouting (MFS) in the hippocampus ...
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Feasibility and toxicity of hematopoietic stem cell transplant in multiple sclerosis
(Mashhad University of Medical Sciences, 2017-07-01)Multiple sclerosis is a debilitating disease of the central nervous system. It affects people of all ages but is more prevalent among 20-40 year olds. Patients with MS can be presented with potentially any neurological ...
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A novel treatment approach for retinoblastoma by targeting epithelial growth factor receptor expression with a shRNA lentiviral system
(Mashhad University of Medical Sciences, 2017-07-01)Objective(s): Non-invasive treatment options for retinoblastoma (RB), the most common malignant eye tumor among children, are lacking. Epithelial growth factor receptor (EGFR) accelerates cell ...
