مرور Volume 22, Issue 7 بر اساس عنوان
در حال نمایش موارد 1 - 14 از 14
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Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, ...
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Asiaticoside attenuates hyperoxia-induced lung injury <i>in vitro</i> and<i>in vivo</i>
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Asiaticoside (AS) displays anti-inflammation, and anti-apoptosis effect, but the role of AS in hyperoxia-induced lung injury (HILI) treatment is undefined. Therefore, the aim of this ...
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Determination of antimicrobial effect of protamine by transmission electron microscopy and SDS PAGE on <i>Pseudomonas aeruginosa</i> isolates from diabetic foot infection
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Diabetic foot infection is one of the major complications of diabetes leading to lower limb amputations. Isolation and identification of bacteria causing diabetic foot infection, ...
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The effect of titanium dioxide nanoparticles on mice midbrain substantia nigra
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Widely used Titanium dioxide nanoparticles (TiO2) enter into the body and cause various organ damages. Therefore, we aimed to study the effect of TiO2 on the substantia nigra of ...
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Effects of nano-copper on maize yield and inflammatory response in mice
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Copper (Cu) is an essential dietary supplement in animal feeds, which plays an important role in maintaining the balance of all living organisms. Copper nanoparticles (nCu) participate ...
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Evaluation of the neuroprotective, anticonvulsant, and cognition-improvement effects of apigenin in temporal lobe epilepsy: Involvement of the mitochondrial apoptotic pathway
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Cognitive deficit is a common problem in epilepsy. A major concern emergent from the use of antiepileptic drugs includes their side effects on learning and memory. Herbal medicine ...
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Exploring the role and inter-relationship among nitric oxide, opioids, and KATP channels in the signaling pathway underlying remote ischemic preconditioning induced cardioprotection in rats
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): This study explored the inter-relationship among nitric oxide, opioids, and KATP channels in the signaling pathway underlying remote ischemic preconditioning (RIPC) conferred ...
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GYY4137 a H2S donor, attenuates ipsilateral epididymis injury in experimentally varicocele-induced rats via activation of the PI3K/Akt pathway
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The current study was aimed to investigate the effect of morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) on ipsilateral epididymis injury in a rat model of ...
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<i>Rhopalurus junceus</i> scorpion venom induces antitumor effect <i>in vitro</i> and <i>in vivo</i> against a murine mammary adenocarcinoma model
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): In Cuba the endemic scorpion species Rhopalurus junceus has been used in traditional medicine for cancer treatment and related diseases. However there is no scientific evidence about ...
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Irisin protect the Dopaminergic neurons of the Substantia nigra in the rat model of Parkinson’s disease
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Exercise ameliorates the quality of life and reduces the risk of neurological derangements such as Alzheimer's (AD) and Parkinson's disease (PD). Irisin is a product of the physical ...
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Kinetics of T cell response in the testes and CNS during experimental autoimmune encephalomyelitis: Simultaneous blood-brain and -testis barrier permeability?
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are regarded as autoimmune diseases of the central nervous system (CNS). The CNS, ...
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Pathogenic interactions between <i>Helicobacter pylori</i> adhesion protein HopQ and human cell surface adhesion molecules CEACAMs in gastric epithelial cells
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The present paper aims to review the studies describing the interactions between HopQ and CEACAMs along with possible mechanisms responsible for pathogenicity of Helicobacter pylori.
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Sesquiterpene fractions of <i>Artemisia</i> plants as potent inhibitors of inducible nitric oxide synthase and cyclooxygenase-2 expression
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Artemisia species are important medicinal plants throughout the world. Some species are traditionally used for their anti-inflammatory effect. The present study was designed to isolate ...
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Toxin profiles and antimicrobial resistance patterns among toxigenic clinical isolates of <i>Clostridioides (Clostridium)</i> difficile
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Clostridioides (Clostridium) difficile infection as a healthcare-associated infection can cause life-threatening infectious diarrhea in hospitalized patients. The aim of this study ...
