Volume 21, Issue 6
مرور بر اساس
ارسال های اخیر
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Role of L-arginine/NO/cGMP/KATP channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): Growing evidence demonstrates that L-arginine/NO/cGMP/KATP channel pathway has a modulatory role in pain perception. Previous studies have shown that thymoquinone exerts antinociceptive ...
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Melatonin ameliorates testicular damages induced by nicotine in mice
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): Nicotine as a toxic substance leads to impairment of the reproductive system function. The aim of this study was to evaluate effects of melatonin on testicular alterations, sperm ...
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Hydroalcoholic extract of flaxseed improves polycystic ovary syndrome in a rat model
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): Herbal medicines are an alternative choice for treatment or controlling of polycystic ovary syndrome (PCOS). Effect of hydroalcoholic extract of flaxseed was evaluated on ovarian ...
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Radiosensitizing effects of Sestrin2 in PC3 prostate cancer cells
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): The stress-responsive genes of Sestrin family are recognized as new tumor suppressor genes in breast carcinoma, however, the function of Sestrin family in human prostate cancer is ...
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Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): Neuroprotection is created following the inhibition of angiotensin II type 1 receptor (AT1R). Therefore, the purpose of this research was examining AT1R blockage by candesartan in ...
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The role of nitric oxide in the protective action of remote ischemic per-conditioning against ischemia/reperfusion-induced acute renal failure in rat
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): We investigated the role of nitric oxide (NO) in the protective effects of remote ischemic per-conditioning (rIPerC) on renal ischemia/reperfusion (I/R) injury in male rats.
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Protective effects of vitamin D on ischemia-reperfusion injury of the ovary in a rat model
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): The aim of the present study is to investigate probable acute effects of vitamin D on ischemia-reperfusion injury in the rat ovary.Materials and Methods: ...
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Cholesteryl ester transfer protein gene variations and macronutrient intakes interaction in relation to metabolic syndrome: Tehran lipid and glucose study
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): There are controversial results regarding the effect of the interaction of CETP polymorphisms with dietary fats on the lipid profiles. The aim of this study was to examine the effect ...
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Selenium supplementation in the form of selenium nanoparticles and selenite sodium improves mature male mice reproductive performances
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): The current study was conducted to examine the possible protective and retentive effects of one-week intra-peritoneal (IP) administration of selenium nanoparticles (Se-NPs), compared ...
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Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): Considering the lack of information, the effects of mild endurance exercise plus blood flow restriction (BFR) on electrocardiographic parameters, hypertrophy index, and expression ...
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Effect of combination therapy with pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury in rats
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): The study was intended to investigate the combined influence of two neuroprotective agents pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury (GCIRI) ...
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The fate of neurons after traumatic spinal cord injury in rats: A systematic review
(Mashhad University of Medical Sciences, 2018-06-01)Objective(s): To reach an evidence-based knowledge in the context of the temporal-spatial pattern of neuronal death and find appropriate time of intervention in order to preserve spared neurons ...
