مرور Volume 19, Issue 3 بر اساس عنوان
در حال نمایش موارد 1 - 13 از 13
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Alteration in cardiac uncoupling proteins and eNOS gene expression following high-intensity interval training in favor of increasing mechanical efficiency
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):High-intensity interval training (HIIT) increases energy expenditure and mechanical energy efficiency. Although both uncoupling proteins (UCPs) and endothelial nitric oxide synthase ...
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Co-treatment by docetaxel and vinblastine breaks down P-glycoprotein mediated chemo-resistance
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Chemoresistance remains the main causes of treatment failure and mortality in cancer patients. There is an urgent need to investigate novel approaches to improve current therapeutic ...
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Designing mucoadhesive discs containing stem bark extract of Ziziphus jujuba based on Iranian traditional documents
(Mashhad University of Medical Sciences, 2016-03-01)Objective (s): Mucoadhesive disc is one of the various routes of drug delivery for curing buccal disease.Materials and Methods:Everydiscs containing 70 mg stem bark extract ...
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Diagnosis of genetic defects through parallel assessment of PLCζ and CAPZA3 in infertile men with history of failed oocyte activation
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Phospholipase C ζ (PLCζ) is considered as a nominee for sperm associated oocyte activating factors and is located back-to-back with CAPZA3, an actin-capping protein controlling actin ...
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The effect of adropin on lipid and glucose metabolism in rats with hyperlipidemia
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):The aim of this study was to evaluate, for the first time, whether the effects of low-dose adropin administration is effective in rats with hyperlipidemia. Materials and ...
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The effect of progesterone treatment after ovarian induction on endometrial VEGF gene expression and its receptors in mice at pre-implatation time
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Progestrone is a prequisite for pre-implantation angiogenesis and induce decidual angiogenesis. It is unknown the effect of progestrone administration on the endometrium of hyperstimulated ...
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Effects of estradiol on reduction of osteoarthritis in rabbits through effect on matrix metalloproteinase proteins
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Osteoarthritis (OA), as a known degenerative joint disease, is the most common form of arthritis. In this study, we aimed to elucidate unclear pathogenesis of OA. Materials ...
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Human papillomavirus and breast cancer in Iran: a meta- analysis
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):This study aims to investigate the relationship between human papillomavirus (HPV) and breast cancer using meta- analysis. Materials and Methods: Relevant ...
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miR-506 inhibits cell proliferation and invasion by targeting TET family in colorectal cancer
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of ...
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Neuroprotective effects of atomoxetine against traumatic spinal cord injury in rats
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):Spinal cord injury (SCI) often causes serious and irreversible neurological deficit leading to disability or impairment of normal physical activity. Atomoxetine, a selective norepinephrine ...
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Nuclear factor erythroid-2 related factor 2 overexpressed mesenchymal stem cells transplantation, improves renal function, decreases injuries markers and increases repair markers in glycerol-induced Acute kidney injury rats
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):Recently cell therapy is a promising therapeutic modality for many types of disease including acute kidney injury (AKI). Due to the unique biological properties, mesenchymal stem cells ...
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Recombinant fibromodulin has therapeutic effects on diabetic nephropathy by down-regulating transforming growth factor-β1 in streptozotocin-induced diabetic rat model
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s):Diabetic nephropathy is an important long-term complication of diabetes mellitus which appears to be partially mediated by an increase in secretion of transforming growth factor-β (TGF-β). ...
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The role of nitric oxide on the oxytocin induce analgesia in mice
(Mashhad University of Medical Sciences, 2016-03-01)Objective(s): Analgesic effects of oxytocin and it's the other physiological effects were well-known. The aim of present study was determination of nitric oxide role on ...
