مرور Volume 19, Issue 2 بر اساس تاریخ انتشار
در حال نمایش موارد 1 - 13 از 13
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Assessment of expressions of Bcl-XL, b-FGF, Bmp-2, Caspase-3, PDGFR-α, Smad1 and TGF-β1 genes in a rat model of lung ischemia/reperfusion
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Ischemia is described as organs and tissues are destitute of oxygen due to decreased arterial or venous blood flow. Many mechanisms play role in cell death happened as a consequence ...
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α-Terpineol attenuates morphine-induced physical dependence and tolerance in mice: role of nitric oxide
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Dependence and tolerance to opioid analgesics are major problems limiting their clinical application. a-Terpineol is a monoterpenoid alcohol with neuroprotective effects which is found ...
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The role of ISCOMATRIX bilayer composition to induce a cell mediated immunity and protection against leishmaniasis in BALB/c mice
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Development of new generation of vaccines against leishmaniasis is possible because long-term protection is usually seen after recovery from cutaneous leishmaniasis. ISCOMATRIX is ...
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Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): Berberine is one of the main alkaloids and it has been proven to have different pharmacological effects including inhibition of cell cycle and progression of apoptosis in various ...
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In vitro and in silico studies of the inhibitory effects of some novel kojic acid derivatives on tyrosinase enzyme
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): Tyrosinase is a key enzyme in pigment synthesis. Overproduction of melanin in parts of the skin results in hyperpigmentation diseases. This enzyme is also responsible for the enzymatic ...
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Essential oils chemical composition, antioxidant activities and total phenols of Astrodaucus persicus
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Astrodaucus persicus, Apiaceae, is used as vegetable or food additive in some parts of Iran. The essential oils of different parts of Astrodaucus persicus from ...
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Effect of coating thickness of iron oxide nanoparticles on their relaxivity in the MRI
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Iron oxide nanoparticles have found prevalent applications in various fields including drug delivery, cell separation and as contrast agents. Super paramagnetic iron oxide (SPIO) ...
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Opium induces apoptosis in Jurkat cells via promotion of pro-apoptotic and inhibition of anti-apoptotic molecules
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): The aim of this study was to determine the important molecules involved in apoptosis induction by opium in Jurkat cell line. Materials and Methods: Jurkat ...
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Cardioprotective effect of royal jelly on paclitaxel-induced cardio-toxicity in rats
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Paclitaxel is a potent chemotherapy agent with severe side effects, including allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which ...
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Evaluation of Δ9-tetrahydrocannabinol metabolites and oxidative stress in type 2 diabetic rats
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): The object of the study is to examine the effects of Δ9-tetrahydrocannabinol (THC) against oxidative stress in the blood and excretion of THC metabolites in urine of type 2 diabetic ...
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Association of -77T>C and Arg194trp polymorphisms of XRCC1 with risk of coronary artery diseases in Iranian population
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): Coronary artery disease (CAD) is the leading cause of death in both male and female worldwide. The main cause of CAD is the atherosclerosis of coronary arteries, which is, mostly ...
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Growth suppression effect of human mesenchymal stem cells from bone marrow, adipose tissue, and Wharton's jelly of umbilical cord on PBMCs
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s):Immunosuppressive property of mesenchymal stem cells (MSCs) has great attraction in regenerative medicine especially when dealing with tissue damage involving immune reactions. The ...
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Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa
(Mashhad University of Medical Sciences, 2016-02-01)Objective(s): This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase ...



