مرور Volume 20, Issue 2 بر اساس تاریخ انتشار
در حال نمایش موارد 1 - 14 از 14
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Toxicology effects of saffron and its constituents: a review
(Mashhad University of Medical Sciences, 2017-02-01)Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main ...
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CFP10: mFcγ2 as a novel tuberculosis vaccine candidate increases immune response in mouse
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Despite treatment with antibiotics and vaccination with BCG, tuberculosis (TB) is still considered as one of the most important public health problems in the world. Therefore, designing ...
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Cytotoxic and apoptotic effects of different extracts of Artemisia biennis Willd. on K562 and HL-60 cell lines
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Artemisia is a genus of herbs and small shrubs forms an important part of natural vegetation in Iran. It has been reported that several Artemisia species possess ...
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Expression pattern of neurotrophins and their receptors during neuronal differentiation of adipose-derived stem cells in simulated microgravity condition
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. Here we investigated the effects of simulated ...
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Exploring the effect of intravenous lipid emulsion in acute methamphetamine toxicity
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): The increasing use of methamphetamine (METH) in the last decades has made it the second most abused drug. Advancs in the area of intravenous lipid emulsion (ILE) have led to its ...
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Gestational diabetes influences retinal Muller cells in rat's offspring
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): The Muller cell is the principal glial cell of the vertebrate retina. The expression of Glial fibrillary acidic protein (GFAP) in the Muller cells was used as a cellular marker for ...
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The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): To explore the correlation between expression patterns and functions of miR-383 and LDHA in hepatocellular cancer (HCC). Materials and Methods: We ...
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Up-regulation of TLR2 and TLR4 in high mobility group Box1-stimulated macrophages in pulpitis patients
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): High Mobility Group Box1 (HMGB1) is a nonhistone, DNA-binding protein that serves a crucial role in regulating gene transcription and is involved in a variety of proinflammatory, ...
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Nicotine-induced damages in testicular tissue of rats; evidences for bcl-2, p53 and caspase-3 expression
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Present study was performed in order to uncover new aspects for nicotine-induced damages on spermatogenesis cell lineage. Materials and Methods: For ...
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AdipoRon may be benefit for atherosclerosis prevention
(Mashhad University of Medical Sciences, 2017-02-01)Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, ...
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Evaluation of the expression of VIII factor and VEGF in the regeneration of non-vital teeth in dogs using propolis
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): The purpose of the present study was the immunohistochemical evaluation of VEGF and VII factors in dog's teeth pulp revascularized with MTA and propolis. Material ...
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In vitro lymphoproliferative response and cytokine production in mice with experimental disseminated candidiasis
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Systemic candidiasis is an infection of Candida albicans (C. albicans) causing disseminated disease and sepsis, invariably when host defenses are compromised. We ...
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Protective role of licochalcone B against ethanol-induced hepatotoxicity through regulation of Erk signaling
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): Oxidative stress has been established as a key cause of alcohol-induced hepatotoxicity. Licochalcone B, an extract of licorice root, has shown antioxidative properties. This study ...
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Gestational diabetes leads to down-regulation of CDK4-pRB-E2F1 pathway genes in pancreatic islets of rat offspring
(Mashhad University of Medical Sciences, 2017-02-01)Objective(s): The link between a hyperglycemic intrauterine environment and the development of diabetes later in life has been observed in offspring exposed to gestational diabetes mellitus (GDM), ...



