مرور Volume 22, Issue 1 بر اساس عنوان
در حال نمایش موارد 1 - 13 از 13
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Computational and pharmacological investigation of novel 1,5-diaryl-1,4-pentadien-3-one derivatives for analgesic, anti-inflammatory and anticancer potential
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): The novel 1,5-diaryl-1,4-pentadien-3-one derivatives were studied for analgesic, anti-inflammatory and anticancer potential to establish their role in pain, inflammatory disorders ...
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Detection of co-harboring OXA-58 and NDM-1carbapenemase producing genes resided on a same plasmid from an <i>Acinetobacter pittii</i> clinical isolate in China
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Acinetobacter pittii has become an emerging opportunistic noscomial pathogen worldwide with multi-drug resistance. In the present study, an A. pittii strain was isolated from ...
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Effects of citral on oxidative stress and hepatic key enzymes of glucose metabolism in streptozotocin/high-fat-diet induced diabetic dyslipidemic rats
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Phytochemicals such as polyphenols, alkaloids, and terpenoids, protect against the development of early stages and complications of diabetes mellitus according to various reports. ...
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Happy New Year 2019, and welcome to Conference of Iranian Medical Journal Editors
(Mashhad University of Medical Sciences, 2019-01-01)
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Histone deacetylase inhibitory and cytotoxic activities of the constituents from the roots of three species of <i>Ferula</i>
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Histone deacetylase inhibitory and cytotoxic activities of 18 naturally occuring terpenoids (ferutinin, stylosin, tschimgine and guaiol), coumarins (umbelliprenin, farnesiferone B, ...
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Hydrogen sulfide treatment protects against renal ischemia-reperfusion injury via induction of heat shock proteins in rats
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Hydrogen sulfide (H2S) attenuates ischemia-reperfusion injury (IRI) in different organs. However, its mechanism of action in renal IRI remains unclear. The present study investigated ...
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Molecular epidemiology of colistin-resistant <i>Pseudomonas aeruginosa</i> producing NDM-1 from hospitalized patients in Iran
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Resistance to carbapenems is the principal reason for the continuing utilization of colistin as a last resort choice for treating the infections resulted from multidrug carbapenem-resistant ...
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Organ toxicity attenuation by nanomicelles containing curcuminoids: Comparing the protective effects on tissues oxidative damage induced by diazinon
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Diazinon (DZ) is an organophosphate pesticide that induces oxidative damage in different organs. The aim of this study was to compare the effectiveness of nanomicelles containing ...
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The predictive role of toll-like receptor-4 genetic polymorphisms in susceptibility to and prognosis of prostatic hyperplasia
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): This study was aimed to evaluate whether single nucleotide polymorphisms (SNPs) of TLR4 and common living habits of prostate hyperplasia (BPH) patients would affect the subjects' ...
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Protective effects of celecoxib on ischemia reperfusion–induced acute kidney injury: comparing between male and female rats
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): There is increasing evidence for the importance of gender in different diseases; however, the role of gender in response to treatments is still unknown. Therefore, this study ...
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Salidroside regulates the expressions of IL-6 and defensins in LPS-activated intestinal epithelial cells through NF-κB/MAPK and STAT3 pathways
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): To reveal the detailed mechanism underlying the functions of salidroside on the inflammation of intestinal epithelial cells during IBD.Materials and Methods: ...
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The therapeutic effect of ozonated olive oil plus glucantime on human cutaneous leishmaniasis
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Leishmaniasis is one of the main health problems in developing countries, caused by intracellular protozoan parasites of the Leishmania genus. Although research has been successful ...
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Worldwide trends in scientific publications on association of gut microbiota with obesity
(Mashhad University of Medical Sciences, 2019-01-01)Objective(s): Recent evidence has shown underlying roles of gut dysbiosis and metabolic endotoxemia in obesity and its complications. Despite the large number of experimental and clinical researches ...
