Nano-Silica phosphoric acid: an efficient catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (thiones) under solvent-free or sonication conditions
چکیده
Two simple protocols for the synthesis of three-component condensation reaction of an aldehyde, β-ketoester and urea or thiourea to obtain the 3, 4-dihydropyrimidin-2(1H)-ones (thiones) using nano silica phosphoric acid are reported. Short reaction times, high yields, reusability of catalyst and easy workup are some advantages of these protocols.
کلید واژگان
Biginelli reaction4-Dihydropyrimidin-2(1H)-ones
4-Dihydropyrimidin-2(1H)-thiones
Heterogeneous catalyst
Multi-component reactions
Nano silica phosphoric acid
Sonication condition
شماره نشریه
1تاریخ نشر
2012-01-011390-10-11
ناشر
Islamic Azad University, Shahreza Branchسازمان پدید آورنده
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I.R.Iran.Department of Chemistry, College of Science, Yazd University, I. R. Iran .
Department of Chemistry, College of Science, Yazd University, I. R. Iran .
شاپا
2252-02362345-4865
