The Development of Quality of Life Questionnaire for Indonesian Breast Cancer Patients: INA-BCHRQoL

Abstract

Introduction: The breast cancer related incidence and mortality rate in Indonesia are included in the top 10 and<br />top 5 highest in the world. A country-specific Health Related Quality of Life measurement tool is required to help<br />clinician observe and improve the management of the disease. Methods: We developed the questionnaire, namely<br />Indonesian Breast Cancer Health Related Quality of Life (INA-BCHRQoL) by incorporating not only the generic<br />variables such as physical, psychological, and social; but also spiritual variable which is suitable for Indonesian<br />population. The questionnaire was validated to the same population using the value of corrected item-total correlation<br />and the value of Cronbach Alpha. Results: Fourty three questions were considerably valid and reliable on evaluating<br />the HRQoL of early state of breast cancer patients in Indonesia as the value of Cronbach Alpha for physical, cognitive,<br />social and spiritual domain were higher than 0.8 and the corrected item-total correlation were also higher than 0.3.<br />Each domain of the questionnaire was not influenced by the treatment options. Twenty four early stage breast cancer<br />(10 FAC based chemotherapy and 14 Taxan based chemotherapy) were enrolled in the main study and the score of<br />HRQOL obtained from INA-BCHRQoL were considerably high. Conclussion: The INA-BCHRQoL questionnaire<br />can be implemented as a valid and reliable tool to assess quality of life in early stage breast cancer patients in Indonesia.