A Comparison of the Dosimetric Parameters of Cs-137 Brachytherapy Source in Different Tissues with Water Using Monte Carlo Simulation

Abstract

Introduction <br/>After the publication of Task Group number 43 dose calculation formalism by the American Association of Physicists in Medicine (AAPM), this method has been known as the most common dose calculation method in brachytherapy treatment planning. In this formalism, the water phantom is introduced as the reference dosimetry phantom, while the attenuation coefficient of the sources in the water phantom is different from that of different tissues. The purpose of this study is to investigate the effects of the phantom materials on the TG-43 dosimetery parameters of the Cs-137 brachytherapy source using MCNP4C Monte Carlo code. <br/>Materials and Methods <br/>In this research, the Cs-137 (Model Selectron) brachytherapy source was simulated in different phantoms (bone, soft tissue, muscle, fat, and the inhomogeneous phantoms of water/bone) of volume 27000 cm3 using MCNP4C Monte Carlo code. *F8 tally was used to obtain the dose in a fine cubical lattice. Then the TG-43 dosimetry parameters of the brachytherapy source were obtained in water phantom and compared with those of different phantoms. <br/>Results <br/>The percentage difference between the radial dose function g(r) of bone and the g(r) of water phantom, at a distance of 10 cm from the source center is 20%, while such differences are 1.7%, 1.6% and 1.1% for soft tissue, muscle, and fat, respectively. The largest difference of the dose rate constant of phantoms with those of water is 4.52% for the bone phantom, while the differences for soft tissue, muscle, and fat are 1.18%, 1.27%, and 0.18%, respectively. The 2D anisotropy function of the Cs-137 source for different tissues is identical to that of water. <br/>Conclusion <br/>The results of the simulations have shown that dose calculation in water phantom would introduce errors in the dose calculation around brachytherapy sources. Therefore, it is suggested that the correction factors of different tissues be applied after dose calculation in water phantoms, in order to decrease the errors of brachytherapy treatment planning. <br/>