A Rare Case of Myeloid Sarcoma Presenting as Nasal Cavity Mass

Abstract

Myeloid Sarcoma (MS) is a tumor mass consisting of myeloblast with or without maturation occurring at an anatomical site other than the bone marrow. Incidence of MS ranges from 1-9% and is most commonly misdiagnosed as Non Hodgkins Lymphoma or poorly differentiated carcinoma. MS can occur in various sites but nasal cavity involvement is rare. Here we report acaseof MS presenting as nasal polyp since 2 weeks in a 30 year old male patient who presented to Otolaryngology department of Father Muller Medical College Hospital, India in 2012. Patient was eventually found to have Acute Myeloid Leukemia (AML). This case highlights the importance of hematological and histological correlation coupled with Immunohistochemistry which is mandatory for the accurate diagnosis of this rare entity.