Synthesis and Antimicrobial Activity of Some New Isatin Derivatives
(ندگان)پدیدآور
Patel, ABari, STalele, GPatel, JSarangapani, Mنوع مدرک
Textزبان مدرک
Englishچکیده
Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene- 3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial activity of compounds was done by the disk diffusion technique. Among the compounds tested, the compound with 5-Br substitution showed the most favourable antimicrobial activity.
کلید واژگان
IsatinIsatin hydrazone
Imidazolone
Antibacterial
Antifungal
شماره نشریه
4تاریخ نشر
2006-10-011385-07-09
ناشر
School of Pharmacy, Shahid Beheshti University of Medical Sciencesشاپا
1735-03281726-6890