• Trahalose Activates Autophagy and Prevents Hydrogen Peroxide-Induced Apoptosis in the Bone Marrow Stromal Cells 

  Darabi, Shahram؛ Noori-Zadeh, Ali؛ Abbaszadeh, Hojjat Allah؛ Rajaei, Farzad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Bone marrow stromal stem cells (BMSCs) play a significant role in cell therapy. These cells quickly die after transplantation to the affected area due to oxidative stress. The natural disaccharide, trehalose which can be ...

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• Reducing Inappropriate Utilization of Albumin: The Value of Pharmacist-led Intervention Model 

  Dastan, Farzaneh؛ Jamaati, Hamidreza؛ Emami, Habib؛ Haghgoo, Roodabeh؛ Eskandari, Raha؛ Hashemifard, Seyedeh Shadab؛ Khoddami, Fatemeh؛ Mirshafiei Langari, Zahra (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Background: Albumin is known as a human blood product, with high cost and limited availability. Several studies have demonstrated the extent in which albumin is being utilized in controversial indications not supported or ...

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• Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial 

  Jafari, Marziye؛ Ala, Shahram؛ Haddadi, Kaveh؛ Alipour, Abbas؛ Mojtahedzadeh, M؛ Ehteshami, Saeid؛ Abediankenari, Saeid؛ Shafizad, Misagh؛ Salehifar, Ebrahim؛ Khalili, Foroogh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin ...

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• The intravitreal Injection of bevacizumab:The review of Our Experience 

  Afarid, Mehrdad؛ Sadeghi Sarvestani, Ali؛ Rahat, Feisal؛ Azimi, Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Aim: Several ocular and systemic complications have been reported after the bevacizumab intravitreal injection. This study aims at reporting the main indications for the bevacizumab intravitreal injection in our center, ...

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• Effect of vitamins B1, B6 and B12 (Neurobion) on diisopropylfluorophosphate–induced delayed neuropathy in mice 

  Ebrahimi, Mohsen؛ Khoshnood, Mohammad Javad؛ Zia-Behbahani, Majid (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Certain organophosphorus esters such as diisopropylfluorophosphate (DFP) cause delayed neuropathy by inhibition of neuropathy target esterase (NTE) keeping neuron in normal function. In this study, effects of neurobion ...

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• Main Factors Affecting Physicians’ Prescribing Decisions: The Iranian Experience 

  sharifnia, sayed hesam؛ mohammadzadeh, mahdi؛ arzani, gelareh؛ Salamzadeh, Jamshid؛ Abolfazli, Seyed Abolfazl؛ zali, alireza؛ Khoshdel, Alireza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Prescription decision making is a complicated phenomenon influenced by many factors including drug strength, the patient's context, prescriber characteristics, health facilities, payment type and pharmaceutical marketing. ...

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• Chronic Exposure of Human Endothelial Progenitor Cells to Diabetic Condition Abolished the Regulated Kinetics Activity of Exosomes 

  Hassanpour, Mehdi؛ Cheraghi, Omid؛ Brazvan, Belal؛ Hiradfar, Amirataollah؛ Aghamohammadzadeh, Nasser؛ Rahbarghazi, Reza؛ Nouri, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  By virtue of lifestyle change, incidence of type 2 diabetes is increasingly being raised with different up-surging pathologies. This condition found to disqualify endothelial progenitor cells during neo-vascularization. ...

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• Clopidogrel Resistance and its Impact on Clinical Outcome of Iranian Patients Undergoing Percutaneous Coronary Intervention 

  Haji Aghajani, Mohammad؛ Kobarfard, Farzad؛ Shojaei, Seyedpouzhia؛ ahmadpour, Fourozan؛ Safi, Olia؛ kazeminia, neda؛ Zarepishe, Naeime؛ Sistanizad, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  The aim of current study was evaluating the frequency of clopidogrel resistance and its impact on clinical outcome of patients in Iranian patients. Patients undergoing percutaneous coronary intervention in Imam Hussein ...

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• Response Surface Methodology for Optimization of Genistein Content in Soy Flour and its Effect on the Antioxidant Activity 

  Abdelrahman, Asmaa؛ El baz, Ashraf؛ Mahrous, Emad؛ Mahrous, Allaa؛ Ibrahim, Ibrahim؛ Abdel-Monem, Azza؛ Yang, Shang-Tian (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Biotransformation of isoflavones glycosides into the aglycone form is essential to attain the maximum bioavailability. The factors affecting deglycosylation of genistin in soy flour using commercial β-glucosidase enzyme ...

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• Evaluation of Chemical Composition and <I>In-vitro</I> Biological Activities of Three Endemic <I>Hypericum</I> Species from Anatolia <I>(H. thymbrifolium, H. spectabile and H. pseudolaeve)</I> 

  EROGLU OZKAN, ESRA؛ Özsoy, Nurten؛ YILMAZ OZDEN, TUGBA؛ Ozhan, Gul؛ MAT, AFIFE (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  In the present work we carried out a phytochemical and biological investigation on three endemic Hypericum species, i.e. Hypericum thymbrifolium, Hypericum spectabile and Hypericum pseudolaeve from Anatolia in order to ...

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• Saffron Induced Relaxation in Isolated Rat Aorta via Endothelium Dependent and Independent Mechanisms 

  Razavi, Marjan؛ Alyasin, Ali؛ Hosseinzadeh, Hossein؛ Imenshahidi, Mohsen (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Crocus sativus L. (saffron) is a widely used food additive for its color and taste. The hypotensive effects of saffron have been shown in previous studies. The aim of this study was to evaluate the mechanism of vasodilatory ...

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• The Synergistic Effects of Celecoxib and Sodium Valproate on Apoptosis and Invasiveness Behavior of Papillary Thyroid Cancer Cell Line <i>In-vitro</I> 

  Fanian, Maryam؛ Bahmani, Maedeh؛ Mozafari, Mojdeh؛ Naderi, Samaneh؛ Alizadeh Zareie, Marziyeh؛ Okhovat, ?Mohammad Ali؛ Saberzadeh, Jamileh؛ Dehshahri, Ali؛ Takhshid, mohammad ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Metastasis to lymph nodes and distant organs is the main challenge in the treatment of papillary thyroid cancer. In the current investigation, we aimed to evaluate the synergistic effects of celecoxib (CX) and sodium ...

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• Perfluorooctanesulfonate (PFOS) Induces Apoptosis Signaling and Proteolysis in Human Lymphocytes through ROS Mediated Mitochondrial Dysfunction and Lysosomal Membrane Labialization 

  Zarei, Mohammad Hadi؛ Hosseini Shirazi, Farshad؛ Aghvami, Marjan؛ Pourahmad, Jalal (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Perfluorinated compounds (PFCs) such as perfluorooctanesulfonate (PFOS) are stable chemicals that accumulate in biological matrix. Toxicity of these compounds including immunotoxicity has been demonstrated in experimental ...

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• Antitumor effects of umbelliprenin in a mouse model of colorectal cancer 

  Naderi Alizadeh, Mohamad؛ Rashidi, Mohsen؛ mahmodinejad, Ahad؛ Moeini Zanjani, Taraneh؛ ziai, Seyed Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Umbelliprenin is a sesquiterpene coumarin with vitro anti-carcinogenic activities. The aim of this study was to investigate the antitumor effects of umbelliprenin in animal models of colorectal cancer. The cytotoxic effects ...

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• Embryo-Protective Effects Of Cerium Oxide Nanoparticles Against Gestational Diabetes in Mice 

  Vafaei-Pour, Zeinab؛ shokrzadeh, Masoumeh؛ Jahani, Monireh؛ Shaki, Fatemeh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Context: Gestational diabetes is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Diabetes during pregnancy increases the incidences of congenital anomalies, in a mother and her embryo. ...

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• Apoptotic effect of morphine, imiquimod and nalmefene on promastigote , infected and uninfected macrophages with amastigote of Leishmania major by flow cytometry 

  Ebrahimisadr, Parisa؛ Ghaffarifar, Fatemeh؛ Horton, John؛ Dalimi, Abdolhosein؛ Sharifi, Zohreh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  The parasites of genus Leishmania are the causative agents of one of the most widespread and devastating diseases. According to follow-up data, these medications may provoke adverse drug reactions, drug resistance, relapse ...

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• Molecular and biochemical evidences for beneficial effects of zinc oxide nanoparticles in modulation of chlorpyrifos toxicity in human lymphocytes 

  Navaei-Nigjeh, Mona؛ Gholami, Mahdi؛ Fakhri-Bafghi, Maryam Sadat؛ Baeeri, Maryam؛ Abdollahi, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Chlorpyrifos (CP), an acetylcholinesterase (AChE) inhibitor, is used throughout the world as an insecticide in agriculture and an eradicating agent for termites around homes. In this present study, CP is considered as an ...

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• Synthesis of linear and cyclic disulfide heptapeptides of Longicalycinin A and evaluation of toxicity on cancerous cells HepG2 and HT-29 

  Houshdar Tehrani, Mohammad Hassan؛ Bamoniri, Abdolhosein؛ Mirjalil, Bi Bi Fatemeh؛ Gholibeikian, Mohammadreza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  In this work, linear and cyclic disulfide heptapeptides of Longicalycinin A have been successfully synthesized by solid phase methodology with Fmoc /t-Bu and solution phase, respectively. 2-Chlorotrityl chloride resin ...

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• Design and Synthesis of 4-flurophthalimides as potential anticonvulsant agents 

  Iman, Maryam؛ Fakhari, Sina؛ jahanpanah, Mohammad؛ Naderi, Nima؛ Davood, Asghar (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  Objective(s): Anticonvulsant activity of phthalimide was discovered in 2000 by molecular hybridization of thalidomide and ameltolide. In our previous research we have reported some new 4-substituted derivatives of phthalimide ...

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• Combined Unfolded Principal Component Analysis and Artificial Neural Network for Determination of Ibuprofen in Human Serum by Three-Dimensional Excitation–Emission Matrix Fluorescence Spectroscopy 

  Bahrami, Gholamreza؛ Nabiyar, Hamid؛ Sadrjavadi, Komail؛ Shahlaei, Mohsen (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-07-01)

  This study describes a simple and rapid approach of monitoring ibuprofen (IBP). Unfolded principal component analysis-artificial neural network (UPCA-ANN) and excitation-emission spectra resulted from spectrofluorimetry ...

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