• Naghibione; A Novel Sesquiterpenoid with Antiplasmodial Effect from Dorema hyrcanum Koso-Pol. Root, a Plant Used in Traditional Medicine 

  Naghibi, Farzaneh؛ Ghafari, Saeideh؛ Esmaeili, Somayeh؛ Jenett-Siems, Kristina (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in vitro (pLDH assay) and in vivo (Peters' 4-days ...

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• Methoxylated Flavones from Salvia Mirzayanii Rech. f. and Esfand with Immunosuppressive Properties 

  Ayatollahi, Abdul Majid؛ Ghanadian, Mustafa؛ Shamsabadipour, sara؛ Mesaik, M. Ahmed؛ Khalid, A. Shukralla؛ Adeli, Fateme (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Aerial parts of Salvia Mirzayanii was extracted with methanol. Methanol extract was suspended in water and defatted with petroleum ether. The defatted part was then partitioned between ethyl acetate and water. The ethyl ...

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• Analgesic, Anti- inflammatory, Anti- lipoxygenase Activity and Characterization of Three Bioactive Compounds in the Most Active Fraction of Leptadenia reticulata (Retz.)Wight & Arn. – A Valuable Medicinal Plant 

  Mohanty, sudipta؛ M, Kumaraswamy؛ Middha, Sushil؛ P, Lokesh؛ S, Balasubramanaya؛ M, Anuradha (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Leptadenia reticulata was reported to be used for several medicinal purposes. The present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of L. reticulata. The ...

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• Linarin Inhibits the Acetylcholinesterase Activity In-vitro and Ex-vivo 

  Feng, Xinchi؛ Wang, Xin؛ Liu, Youping؛ Di, Xin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Linarin is a flavone glycoside in the plants Flos chrysanthemi indici, Buddleja officinalis, Cirsium setosum, Mentha arvensis and Buddleja davidii, and has been reported to possess analgesic, antipyretic, anti-inflammatory ...

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• Phytochemical and Antioxidant Investigation of the Aerial Parts of Dorema glabrum Fisch. & C. A. Mey 

  Delnavazi, Mohammad-Reza؛ hadjiakhoondi, abbas؛ Delazar, Abbas؛ Ajani, Yousef؛ Tavakoli, Saeed؛ Yassa, Narguess (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Dorema glabrum Fisch. & C.A. Mey. (Apiaceae) is a monocarpic perennial plant distributed in southern Caucasus. In Azerbaijan Republic folk medicine, the gum-resin of this species is used as a diuretic and anti-diarrheal ...

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• Isolation and Characterization of a New Thermoalkalophilic Lipase from Soil Bacteria 

  Rabbani, Mohammed؛ shafiee, fatemeh؛ Shayegh, Zahra؛ mir mohammad sadeghi, hamid؛ Samsam Shariat, Ziaedin؛ Etemadifar, zahra؛ Moazen, Fatemeh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Lipases are diversified enzymes in their properties and substrate specificity, which make them attractive tools for various industrial applications. In this study, an alkaline thermostable lipase producing bacteria were ...

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• Enhanced Production of Insulin-Like Growth Factor I Protein in Escherichia coli by optimization of five key factors 

  Ranjbari, Javad؛ Babaeipour, Valiollah؛ Vahidi, Hossein؛ Moghimi, Hamidreza؛ Mofid, MohammadReza؛ Namvaran, MohammadMehdi؛ Jafari, Sevda (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Abstract Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. The major objective of this study is over- production of recombinant human insulin-like growth factor ...

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• Warfarin-induced Eosinophilia in a child with Burkitt Lymphoma: A Case Report 

  Goudarzipour, Kourosh؛ Ghazizadeh, Farid؛ Hoseini Tavasol, Hesameddin؛ Behnam, Behdad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  An important complication of chemotherapy is thromboembolic events that can occur during treatment course. In this way, Warfarin can be used as an efficient prophylactic agent to prevent these complications. Although ...

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• A Randomized, Double-blind, Placebo-controlled Trial of Celecoxib Augmentation of Sertraline in Treatment of Drug-naive Depressed Women: A Pilot Study 

  Majd, Marzieh؛ Hashemian, Farshad؛ Hosseini, Seyed Mohammad؛ Vahdat Shariatpanahi, Maryam؛ Sharifi, Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  This study was designed to examine the antidepressant effect of celecoxib (200 mg/day) augmentation of sertraline in the treatment of female patients with first episode of major depression over 8 weeks of therapy.Thirty ...

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• Comparison between Prothrombin Complex Concentrate (PCC) and Fresh Frozen Plasma (FFP) for the Urgent Reversal of Warfarin in Patients with Mechanical Heart Valves in a Tertiary Care Cardiac Center 

  Golpira, Reza؛ Farsad؛ Najafi, Hamideh؛ Totonchi, Ziya؛ Salajegheh, Shirin؛ Bakhshandeh, Hooman؛ hashemian, Farshad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Fresh frozen plasma (FFP) and prothrombin complex concentrate (PCC) reverse oral anticoagulants such as Warfarin. We compared the standard dosage FFP and PCC in terms of efficacy and safety for patients with mechanical ...

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• Topical Turmeric Microemulgel in the Management of Plaque Psoriasis; A Clinical Evaluation 

  Sarafian, Golnaz؛ Afshar, Minoo؛ Mansouri, Parvin؛ Asgarpanah, Jinous؛ Raoufinejad, Kosar؛ Rajabi, Mehdi (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Psoriasis is an autoimmune and recurrent chronic inflammatory skin disease. About 1-3% of the world wide populations are affected. The characteristic features are hyperprolifration of keratinocytes leading to redness, ...

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• Discrimination of Human Cell Lines by Infrared Spectroscopy and Mathematical Modeling 

  Zendehdel, Rezvan؛ Hosseini Shirazi, Farshad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Variations in biochemical features are extensive among cells. Identification of marker that is specific for each cell is essential for following the differentiation of stem cell and metastatic growing. Fourier transform ...

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• Study of the Effects of ATP Suppliers and Thiol Reductants on Toxicity of Pioglitazone in Isolated Rat Liver Mitochondria 

  Rezaeian Mehrabadi, Abbas؛ Jamshidzadeh, Akram؛ RAshedinia, Marzieh؛ Niknahad, Hossein (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, ...

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• Effect of Biomolecular Conformation on Docking Simulation: A Case Study on a Potent HIV-1 Protease Inhibitor 

  Razzaghi-Asl, Nima؛ Sepehri, Saghi؛ ebadi, ahmad؛ Miri, Ramin؛ Shahabipour, Sara (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease pertained to the human immune system. Given its crucial role in viral replication, HIV-1 protease (HIV-1 PR) is a prime ...

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• Protective Role of Rheum tanguticum Polysaccharides 1 on Radiation-Induced Intestinal Mucosal Injury 

  Zhang, Zhi-Pei؛ Liu, Lin-Na؛ Shi, Lei؛ Li, Shi-Cao؛ Zhang, Wen-Juan؛ Zhang, Yan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  The protective effects of Rheum tanguticum polysaccharide 1 (RTP1), which is extracted from the Chinese traditional medicine Rheum tanguticum, on radiation-induced intestinal mucosal injury was investigated. Rat intestinal ...

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• Ameliorating of Memory Impairment and Apoptosis in Amyloid β-Injected Rats Via Inhibition of Nitric Oxide Synthase: Possible Participation of Autophagy 

  Shariatpanahi, Marjan؛ Khodagholi, Fariba؛ Ashabi, Ghorbangol؛ Aghazadeh Khasraghi, Azar؛ Azimi, Leila؛ Abdollahi, Mohammad؛ Ghahremani, Mohammad Hossein؛ Ostad, Seyed Naser؛ Noorbakhsh, farshid؛ Sharifzadeh, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  It has been proposed that appearance of amyloid beta (Aβ) in hippocampus is one of the characteristic features of Alzheimer's disease (AD). The role of Nitric oxide (NO) in neurodegenerative disorders is controversy in ...

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• Computational Study of Quinolone Derivatives to Improve their Therapeutic Index as Anti-malaria Agents: QSAR and QSTR 

  Iman, Maryam؛ Davood, Asghar؛ Khamesipour, Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Malaria is a parasitic disease with limited chemotherapy options. Chemotherapy options are limited; moreover, drug resistant frequently occurs. The speed of drug development should be faster to overcome the emerging drug ...

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• Synthesis and Antimicrobial Activity of some Tetrahydro Quinolone Diones and Pyrano[2,3-d]pyrimidine Derivatives 

  Shahi, Masoume؛ Foroughifar, Naser؛ Mobinikhaledi, Akbar (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  There has been special interest in the chemistry of quinolone and pyrimidine derivatives due to their diverse biological activities such as anticonvulsant, anti-malarial agents, antibacterial, antiviral, cytostatic, ...

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• Preconcentration and Determination of Mefenamic Acid in Pharmaceutical and Biological Fluid Samples by Polymer-grafted Silica Gel Solid-phase Extraction Following High Performance Liquid Chromatography 

  Bagheri Sadeghi, Hayedeh؛ Ahmad Panahi1, Homayon؛ Mahabadi, Mahsa؛ Moniri, Elham (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  Abstract Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that has analgesic,anti-infammatory and antipyretic actions. It is used to relieve mild to moderate pains. Solid-phase extraction of mefenamic acid ...

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• Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry 

  Asgari, Arezoo؛ Ostad Gholami, Mahsa؛ Keyhanfar, Fariborz؛ Mohebbi, Shohreh؛ Nobarani, Maryam (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2015-07-01)

  In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase ...

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