Volume 13, Issue 2
مرور بر اساس
ارسال های اخیر
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Effect of Boswellia Thurifera Gum Methanol Extract on Cytotoxicity and P53 Gene Expression in Human Breast Cancer Cell Line
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Abstract Boswellia has been widely used in traditional medicine for the treatment of different diseases such as cancer in Iran. The aim of this study was to evaluate the effect of the gum methanol extract of Boswellia ...
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Edaravone Decreases Paraquat Toxicity in A549 Cells and Lung Isolated Mitochondria
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. Paraquat (PQ) is a toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial ...
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Inhibition of NR2B-Containing N-methyl-D-Aspartate Receptors (NMDARs) in Experimental Autoimmune Encephalomyelitis, a Model of Multiple Sclerosis
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity ...
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Effect of Dexamethasone, Insulin and EGF on the Myogenic Potential on Human Endometrial Stem Cell
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Human endometrium contains mesenchymal stem cells (eMSC) which have the ability to differentiate into three cell lineages and the potential in therapeutic applications. We hypothesize that using environmental induction in ...
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Evaluation of CYP2C9 activity in rats: use of tolbutamide alone and in combined with bupropion
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)A “cocktail"of several probe drugs is often used to evaluate metabolic activity of multiple cytochrome P450 enzymes in one session. Some interactions among probe drugs can appear and may impact the rate of biotransformation ...
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Imbalanced Diet Deficient in Calcium and Vitamin D- Induced Juvenile Osteopenia in Rats; the Potential Therapeutic Effect of Egyptian Moghat Roots Water Extract (Glossostemon bruguieri)
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)This study aimed to explore and validate a new juvenile osteopenic (JO) rat model then examine the efficacy of moghat (Glossostemon bruguieri) as an alternative reversal therapy for JO. Phytochemical screening analysis ...
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Does Long-Term Administration of a Beta-Blocker (Timolol) Induce Fibril-Based Cataract Formation In-vivo?
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Timolol is a non-selective beta-adrenergic receptor antagonist administered for treating glaucoma, heart attacks and hypertension. In the present study, we set out to determine whether or not timolol can provoke cataract ...
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Synergistic activity of econazole-nitrate and chelerythrine against clinical isolates of Candida albicans
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)The aim of this investigation was to assess the in vitro interaction of two antifungal agents, econazole-nitrate and chelerythrine, against ten fluconazole-resistant clinical isolates and one ATCC type strain 10231 of ...
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Comparing Docetaxel Plus Cisplatin with Paclitaxel Plus Carboplatin in Chemotherapy-Naïve Patients with Advanced Non-Small-Cell Lung Cancer: a Single Institute Study
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Aims: The backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. We intended to compare the effectiveness of two commonly used regimens in real world practice. Methods: This ...
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Evaluation of Residual Diazinon and Chlorpiryfos in Children Herbal Medicines by Headspace-SPME and GC-FID
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)AbstractThe oldest method for the managing of the illness is the use of medicinal plants. The use of herbal products as the first choice in self-treatment of minor conditions continues to expand rapidly across Iran. This ...
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Total phenolic contents and antioxidant activities of different extracts and fractions from the aerial parts of Artemisia biennis Willd
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Total phenolic contents (TPC) of five different extracts (petroleum ether, dichloromethane, ethyl acetate, ethanol and ethanol-water) of Artemisia biennis Willd were measured in this work. The antioxidant activity was ...
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Anti-viral evaluation of sesquiterpene coumarins from Ferula assa-foetida against HSV-1
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while ...
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HPTLC Analysis, Antioxidant, and Antigout Activity of Six Indian Medicinal Plants
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)The HPTLC analysis, antioxidant, and antigout activity of Asparagus racemosus, Withania somnifera, Vitex negundo, Plumbago zeylanica, Butea monosperma and Tephrosia purpurea extracts were investigated. The chemical ...
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Total Phenolic Content and Antibacterial Activity of Five Plants of Labiatae against Four Foodborne and Some Other Bacteria
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)The aim of this study was to evaluate the antibacterial effects of Thymus vulgaris, Thymus caramanicus, Zataria multiflora, Ziziphora clinopodioides and Ziziphora tenuior against four foodborne and four other bacteria ...
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Synthesis and Anticonvulsant Evaluation of some New 6-(Substitutedphenyl) thiazolo[3,2-b][1,2,4]triazole Derivatives in Mice
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Epilepsy is the most frequnt nearological affiction and afflicts 1% about of the worlds population. Currently there is an urgent need for the development of novel anticonvulsants with higher levels of potency and lower ...
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Systematic analysis of main constituents in rat biological samples after oral administration of the methanol extract of Fructus Aurantii by HPLC-ESI-MS/MS
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)High performance liquid chromatography (HPLC) with diode array detection (DAD) and electrospray ionization tandem mass spectrometry (ESI/MS/MS) was used to analyze the main components in the methanol extract of Fructus ...
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Molluscicidal Activity of the Methanol Extract of Callistemon Viminalis (Sol.Ex Gaertner) G.Don Ex Loudon Fruits, Bark and Leaves against Biomphalaria Alexandrina Snails
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)Methanol extracts of Callistemon viminalis (Sol. Ex Gaertner) G.Don Ex Loudon fruits, bark and leaves were tested for molluscicidal activity. Snails were collected and kept in dechlorinated water under standard condition. ...
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Liquid Chromatography Tandem Mass/Mass Spectrometry for the Quantification of Fudosteine in Human Serum without Precolumn Derivatization
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)A quantitative analysis method for fudosteine in human serum by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (HPLC-ESI/MS/MS) was established, which shows high sensitivity and ...
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Computational Aided-Molecular Imprinted Polymer Design for Solid Phase Extraction of Metaproterenol from Plasma and Determination by Voltammetry Using Modified Carbon Nanotube Electrode
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)A molecular imprinted polymer (MIP) was computationally designed and synthesized for the selective extraction of metaproterenol (MTP), from human plasma. In this regards semi empirical MP3 and mechanical quantum (DFT) ...
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GC-FID and HPLC-DAD Methods for the Determination of Menadione Sodium Bisulphite Directly and by Converting Menadione Sodium Bisulphite to Menadione in Pharmaceutical Preparation
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2014-06-01)GC-FID and HPLC-DAD were developed for determination of menadione (MN) and menadione sodium bisulphite (MSB). By means of each method, quantitative analysis of MSB in commercial pharmaceutical was performed in both direct ...



