Eysenhardtia polystachya is widely used in folk medicine as an anti-rheumatic and analgesicagent, but no systematic study of its effects on several markers associated with rheumatoidarthritis and its ethnomedical use as ...

The anti-hypercholesterolemic effect of berbamine (BBM) isolated from Rhizoma Coptidis (RC) was investigated in hypercholesterolemic zebrafish model induced by high-cholesterol (HC) diet. Zebrafish embryo assay revealed ...

The aim of the present study was to determine cytotoxic activity of crude methanolicextract of Echinophora platyloba on breast cancer MDA-MB-231 cell line. The free radicalscavenging effects of methanolic extract of E. ...

The Stober process is frequently used to prepare silica-coated iron oxide nanoparticles. This is usually achieved by seeding a reaction mixture consisting of water, ethanol and a catalyst with iron oxide particles and ...

The essential oils obtained by hydrodistillation from the stem, leaf and flower of Phlomis aucheri Boiss., which is endemic to Iran, stem, leaf and root of Teucrium polium L. and solvent free microwave extraction oil from ...

Selective COX-2 inhibitors are most widely used analgesic and anti-inflammatory drugs;however, its maximal use is highly associated with various serious abnormal cardiovascularevents. Beraprost sodium (BPS), prostacyclin ...

Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the ...

In communities which consume rice as main food, importance of risk assessment forcontaminants is always taken into consideration by health authorities. The present study isan attempt for monitoring of 56 pesticides from ...

Human hepatocellular carcinoma is one of the most common recurrent malignancies, for as much as, there is no effective therapy. Silibinin, a widely used drug and supplement for various liver disorders, demonstrated anticancer ...

The genus Achillea (Asteraceae) consists of important medicinal species, growing wildly in Iran, of which A. tenuifolia is found in Iran-o-Turan regions. Regarding the traditional use of Achillea species for treatment of ...

The most common malignant neoplasm of the head and neck region is laryngeal cancerwhich presents a significant international health problem. The present study aims to screenpotential proteins related to laryngeal cancer ...

In this research, aerial parts of Euphorbia denticulata Lam were collected from Sanandaj city in Kurdistan province at the West of Iran. It was extracted by maceration using acetone as solvent. Isolation of compounds were ...

Ginseng is now used worldwide as a traditional Oriental medicine. Ginsenosides, alsoknown as ginseng saponins, are responsible for most pharmacological efficacies of ginseng.This work aimed to assess the novel skin ...

DHIPC (2,4-dichloro-2´-hydroxyl-4´,6´-diisoprenyloxychalcone) is a new chalconecompound. In this study, its antidepressant-like activity of compound DHIPC was evaluated bythe forced swimming test and the tail suspension ...

The interest in the synthesis of metallic complexes of different drugs to make them moreefficient in biological environment of the human body is seen for the last few decades. Widerange of metal complexes are already used ...

Insulin hormone is an important part of the endocrine system. It contains two polypeptide chains and plays a pivotal role in regulating carbohydrate metabolism. Insulin receptors (IR) located on cell surface interacts with ...

Nepeta (Lamiaceae) is an important genus with beneficial medicinal properties. N. sintenisiiBornm. has been used in folk medicine of Iran to cure various diseases. We investigated theanti-melanogenesis effects of n-hexane, ...

The aim of the present study was to formulate β-cyclodextrin (β-CD) nanoparticles loaded with geraniol (GR) essential oil (EO) with appropriate physicochemical properties. Complexation of GR with β-CD was optimized by ...

A new series of peptide-like derivatives containing different aromatic amino acids andpossessing pharmacophores of COX-2 inhibitors as SO2Me or N3 attached to the para positionof an end phenyl ring was synthesized for ...

Cardiosphere-derived cells (CDCs) have emerged as one of the most promising stem cell types for cardiac protection and repair. Exosomes are required for the regenerative effects of human CDCs and mimic the cardioprotective ...