Volume 11, Issue 1
مرور بر اساس
ارسال های اخیر
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Cytotoxic Effects of two Iranian Scorpions Odontobuthusdoriae and Bothutus saulcyi on Five Human Cultured Cell lines and Fractions of Toxic Venom
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Scorpion venom toxicity is of major concern due to its influence on human activities and public health. We investigated the in-vitro process of cell death caused by two Iranian scorpions Odontobuthus doriae and Bothutus ...
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Fluoxetin Competes with Cortisol for Binding to Human Serum Albumin
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Human serum albumin (HSA) is an important protein that carries variety of substances like some hormones and drugs in blood. Pharmacological studies of the interaction of many drugs and HSA are reported during several ...
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Selective Cyclooxygenase-2 Inhibitor Compound 11b Improves Haloperidol-Induced Catatonia by Enhancing the Striatum Dopaminergic Neurotransmission
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The aim of this research was to investigate the Cyclooxygenase-2 (COX-2) selective inhibition effect on haloperidol-induced catatonia. In this study, the effect of orally, acutely and Sub-chronically administrations of ...
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The Time Course of JNK and P38 Activation in Cerebellar Granule Neurons following Glucose Deprivation and BDNF Treatment
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Low glucose condition induces neuronal cell-death via intracellular mechanisms including mitogen-activated protein kinases (MAPK) signaling pathways. It has been shown that low glucose medium decreases neuronal survival ...
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Effects of Teucrium polium Ethylacetate Extract on Serum, Liver and Muscle Triglyceride Content of Sucrose-induced Insulin Resistance in Rat
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Possessing putative hypolipidemic effects, Teucrium polium (TP) have been traditionally used as a medicinal plant in Iran. The aim of the present study was to investigate this effect on the sucrose-induced insulin resistance ...
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Role of Serotonergic System on Modulation of Depressogenic-Like Effects of Silymarine
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and ...
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A Comparison between Sedative Effect of Propofol-Fentanyl and Propofol-Midazolam Combinations in Microlaryngeal Surgeries
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Considering the growing trend of laryngeal surgeries and the need to protect the airway during and after surgery, among several therapeutic regimens to induce sedation, two regimens of propofol-fentanyl and propofol-midazolam ...
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Effect of Pimpinella tirupatiensis on Oxidative Enzymes in STZ-induced Diabetic Rat Kidney
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The present study was aimed to evaluate the therapeutic potential of Pimpinella tirupatiensis (Pt) by assaying the activities of selective mitochondrial enzymes in streptozotocin induced diabetic rats. Diabetic rats showed ...
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Antioxidant Potential of Fagonia arabica Against Chemical Ischemia Induced in PC12 Cells
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The imbalance between pro-oxidants and anti-oxidants leads to generation of oxygen/nitrogen free radicals which are implicated in several neurodegenerative diseases. Fagonia arabica is an ethno-pharmacologically important ...
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Evaluation of Carbamazepine (CBZ) Supersaturatable Self-Microemulsifying (S-SMEDDS) Formulation In-vitro and In-vivo
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The supersaturatable self-microemulsifying drug delivery system (S-SMEDDS) represents a new thermodynamically stable formulation approach wherein it is designed to contain a reduced amount of surfactant and a water-soluble ...
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Involvement of Four Different Intracellular Sites in Chloroacetaldehyde- Induced Oxidative Stress Cytotoxicity
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Chloroacetaldehyde (CAA) is a chlorination by-product in finished drinking water and a toxic metabolite of a wide variety of industrial chemicals (e.g. vinyl chloride) and chemotherapeutic agents (e.g. cyclophosphamide and ...
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Cisplatin Resistant Patterns in Ovarian Cell Line Using FTIR and Principle Component Analysis
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Cisplatin is a common chemotherapeutic agent that used for treatment of many solid cancers. Rapid identification of chemotherapy resistance is very important and may lead to effective treatment plan. Spectroscopy techniques, ...
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Exposure Assessment of the Tehran Population (Iran) to Zearalenone Mycotoxin
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Zearalenone (ZEA) mycotoxin is a potent estrogenic metabolite. It is the primary toxin causing infertility, abortion or other breeding problems. A HPLC method was validated for ZEA in foods using a monolithic column with ...
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Synthesis and Vasorelaxant Effect of 9-aryl-1,8-acridinediones as Potassium Channel Openers in Isolated Rat Aorta
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)ATP-sensitive potassium (KATP) channel openers have a relaxation effect due to the lower cellular membrane potential and inhibit calcium influx. There has been considerable interest in exploring KATP channel openers in the ...
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Developing a Suitable Model for Supplier Selection Based on Supply Chain Risks: An Empirical Study from Iranian Pharmaceutical Companies
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The supply chain represents the critical link between the development of new product and the market in pharmaceutical industry. Over the years, improvements made in supply chain operations have focused largely on ways to ...
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Vancomycin Utilization Evaluation at Hematology-Oncology Ward of a Teaching Hospital in Iran
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The aim of the present study was to evaluate the pattern of vancomycin administration in the hematology-oncology ward of Nemazee Hospital, Shiraz, Iran. Study criteria were developed to assess the several parameters involved ...
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Introduction of Medicinal Plants Species with the Most Traditional Usage in Alamut Region
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The ethnobotany of the medicinal plants of Alamut region is important in understanding the cultures and traditions of Alamut people. This study documents 16 medicinal plant species, most commonly used by the indigenous ...
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Physical and Chemical Stability of Mycophenolate Mofetil (MMF) Suspension Prepared at the Hospital
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)To evaluate the physical and chemical stability of a suspension of mycophenolate mofetil (MMF) prepared in the hospital from commercially available MMF capsules and tablets. Extemporaneous pharmacy was used as a feasible ...
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Phytochemical Analysis and Metal-chelation Activity of Achillea tenuifolia Lam.
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)Achillea tenuifolia Lam. (Asteraceae) afforded a dichloromethane fraction from which three known compounds β-sitosterol (compound1), 5-hydroxy, 4',6,7– trimethoxy flavone (salvigenin compound 2), and methyl-gallate ...
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Search for Proteins in the Liquid Extract of Edible Mushroom, Agaricus bisporus, and Studying their Antibacterial Effects
(School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2012-03-01)The edible mushrooms (basidomycetes) have high nutritional value, promote the immune system, and as a source of natural antimicrobial substances have been used to cure bacterial infections since ancient times.Various kinds ...



