Positron emission tomography (PET) as the functional component of current hybrid imaging (like PET/CT or PET/MRI) seems to dominate the horizon of medical imaging in coming decades. 18Flourodeoxyglucose(18FDG) is the most ...

4-Hydroxynonenal (4-HNE) is a stable end product of lipid peroxidation, which has been shown to play animportant role in cell signal transduction, while increasing cell growth and differentiation. 4-HNE could inhibitphosphatase ...

Chemotherapy is a major therapeutic approach for malignant neoplasms; however, due to the mostcommon adverse events of nausea and vomiting, scheduled chemotherapeutic programs may be impeded oreven interrupted, which ...

Background: This study aimed to identify any association between the p73 gene G4C14-to-A4T14 polymorphismand risk of non-small cell lung cancer (NSCLC) in the south of China. Materials and Methods: We ...

MicroRNA-27a is highly expressed in cancers and has been identified as an oncogenic microRNA. A geneticvariant in pre-miR-27a (rs895819) with a transition of A to G has been demonstrated to be associated with cancerrisk; ...

RASSF1A, regarded as a candidate tumor suppressor, is frequently silenced and inactivated by methylation ofits promoter region in many human tumors. However, the association between RASSF1A promoter methylationand lung ...

Background: Megestrol acetate (MA) is a steroid origin medicine often used for control of cachexia in oncologicpalliative care. Thrombosis is a common problem in oncology patients. One question is whether MA can ...

Background: Molecular prognostic markers have been under investigation for the last decade and novalidated marker to date has been proven to be used in daily clinical practice for urinary bladder cancers. Theaim of ...

Background: Cervical cancer has become a major public health problem worldwide. Iran, like other developingcountries, is facing a number of challenges in managing the disease. This qualitative study documents ...

Objective: To explore the clinical effects of nimotuzumab combined with chemotherapy in the treatment oflate gastric cancer. Methods: A total of 34 reoccurrence or metastatic patients with late stage ...

Objective: To observe treatment effects and safety of fluvoxamine combined with oxycodone prolonged-releasetablets in treating patients with moderate to severe cancer pain. Methods: Patients confirmed ...

Background: The incidence rate of brain tumors has increased more than 40% in the past 20 years, especiallyin adults. We aimed to study the clinical and pathological findings of central nervous system (CNS) tumor ...

Forkhead-box (FOX) transcription factors comprise a large gene family that contains more than 50 membersin man. Extensive studies have revealed that they not only have functions in control of growth and development,but ...

Background and Aim: Breast cancer (BC) is a heterogeneous disease and cell proliferation markers may helpto identify subtypes of clinical interest. We here analyzed the correlation between cell proliferation determinedby ...

Genetic polymorphisms in homologous recombination repair genes cause an abnormal development ofcancerous cells. In the present study we evaluated the possibility of breast cancer association with single nucleotidepolymorphisms ...

Easter Island is a small island of 180 km2, located 3,800 km from the Chilean coast and one of the mostisolated inhabited places in the world. Since the mid-twentieth century, it has been undergoing an epidemiologicaltransition ...

Background: This study was planned in an attempt to develop scales for the assessment of fatigue in pediatriconcology patients aged 7-12 as well as for their parents. Materials and Methods: In collecting ...

Breast cancer is the most common cancer among females worldwide and a most prevalent malignancy inIranian women. Chronic stress may make an important contribution to cancer, especially in the breast. Numerousstudies showed ...

Background: Colon cancer is the second most common cancer in developed countries. Activated plateletsplay a key role in inflammation and atherothrombosis, with mean platelet volume (MPV) is an early markerof platelet ...

The esophageal squamous cell carcinoma (ESCC) is thought to develop through a multi-stage process.Epigenetic gene silencing constitutes an alternative or complementary mechanism to mutational eventsin tumorigenesis. ...