Volume 15, Issue 16
مرور بر اساس
ارسال های اخیر
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Apoptotic Effects of psiRNA-STAT3 on 4T1 Breast Cancer Cells in Vitro
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The aim of this study was to investigate the effect of a Lipofectamine2000 (Life2000) Transfection Reagent transfected psiRNA-STAT3 plasmid on 4T1 breast cancer cells. Materials and Methods: ...
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Combined Effects of Six Cytokine Gene Polymorphisms and SNP-SNP Interactions on Hepatocellular Carcinoma Risk in Southern Guangxi, China
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Cytokine gene single nucleotide polymorphisms (SNPs) are involved in the genesis and progression of hepatocellular carcinoma (HCC). We hypothesized that combined effects of cytokine gene SNPs and SNP-SNP interactions are ...
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Increased Frequency of Micronuclei in Binucleated Lymphocytes among Occupationally Pesticide-exposed Populations: A Metaanalysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The cytokinesis-block micronucleus (CBMN) assay is a standard cytogenetic tool employed to evaluate chromosomal damage subsequent to pesticide exposure. Objectives: To evaluate the pooled ...
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MiRNA-15a Mediates Cell Cycle Arrest and Potentiates Apoptosis in Breast Cancer Cells by Targeting Synuclein-γ
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Recent studies have indicated that microRNA-15a (miR-15a) is dysregulated in breast cancer (BC). We aimed to evaluate the expression of miR-15a in BC tissues and corresponding para-carcinoma tissues. We ...
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Epidemiological Assessment of Leukemia in Kazakhstan, 2003-2012
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Cancer is a major health problem facing the entire world, and Kazakhstan is not the exception. The aim of this study was to present an epidemiological assessment of leukemia in the population of Kazakhstan during 2003-2012. ...
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One-year Survival Rate of Patients with Primary Malignant Central Nervous System Tumors after Surgery in Kazakhstan
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)This study was conducted to evaluate the one-year survival rate of patients with primary malignant central nervous system (CNS) tumors after surgical treatment in Kazakhstan. Retrospective data of patients undergoing ...
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Utility of Nuclear Morphometry in Effusion Cytology
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The cytological analysis of serous effusions is a common investigation and yields important diagnostic information. However, the distinction of reactive mesothelial cells from malignant cells can sometimes ...
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The CCND1 G870A Gene Polymorphism and Leukemia or Non-Hodgkin Lymphoma Risk: a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)In recent years, mounting evidence has indicated that the CCND1 G870A gene polymorphism, which impacts the mitotic cell cycle, may influence leukemia or non-Hodgkin lymphoma risk. Unfortunately, the previous results were ...
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Lack of Relation of Survivin Gene Expression with Survival and Surgical Prognostic Factors in Endometrial Carcinoma Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The relation of survivin gene expression to survival and surgical prognostic factors in the patients with endometrial carcinoma is unclear. Materials and Methods: In this study, 62 cases who ...
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Activity and Expression Pattern of NF-κB /P65 in Peripheral Blood from Hepatocellular Carcinoma Patients - Link to Hypoxia Inducible Factor -1α
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Hepatocellular carcinoma is a complex and heterogeneous tumor with poor prognosis due to frequent intrahepatic spread and extrahepatic metastasis. The molecular mechanisms underlying HCC pathogenesis ...
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Epidemiological Characteristics and Prediction of Esophageal Cancer Mortality in China from 1991 to 2012
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: To analyze the mortality distribution of esophageal cancer in China from 1991 to 2012, to forecast the mortality in the future five years, and to provide evidence for prevention and treatment of esophageal ...
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Sulfasalazine Induces Autophagic Cell Death in Oral Cancer Cells via Akt and ERK Pathways
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Sulfasalazine (SSZ) is an anti-inflammatory drug that has been used to treat inflammatory bowel disease and rheumatoid arthritis for decades. Recently, some reports have suggested that SSZ also has anti-cancer properties ...
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Association between ABCB1 Immunohistochemical Expression and Overall Survival in Gastric Cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Gastric cancer (GC) is one of the most common malignancies worldwide. The ABCB1 protein, a member of the ATP-binding cassette (ABC) transporter family, encoded by the ABCB1 gene, considerably influences the distribution ...
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Type-specific Prevalence of Human Papillomavirus by Cervical Cytology among Women in Brasov, Romania
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)The oncogenic role of human papillomavirus (HPV) in triggering cervical cancer, the second most common cancer in women worldwide, is well established. Romania ranks in first place in Europe in terms of the incidence of ...
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TP53 Polymorphisms in Sporadic North Indian Breast Cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The purpose of this study was to evaluate the potential association of five (p.P47S, p.R72P, PIN3 Ins16bp, p.R213R and r.13494g>a) polymorphisms of TP53 with the risk of developing breast cancer in North ...
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Roles of Neutrophil/Lymphocyte and Platelet/Lymphocyte Ratios in the Early Diagnosis of Malignant Ovarian Masses
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The present study aimed to investigate the utility and importance of the various parameters of complete blood count panel for benign-malignant differentiation of adnexal masses. Materials and ...
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Shortest Path Analyses in the Protein-Protein Interaction Network of NGAL (Neutrophil Gelatinase-associated Lipocalin) Overexpression in Esophageal Squamous Cell Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)NGAL (neutrophil gelatinase-associated lipocalin) is a novel cancer-related protein involves multiple functions in many cancers and other diseases. We previously overexpressed NGAL to analyze its role in esophageal ...
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Curcumin Analogue A501 induces G2/M Arrest and Apoptosis in Non-small Cell Lung Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Curcumin and its analogues have been reported to exert anti-cancer activity against a variety of tumors. Here, we reported A501, a new curcumin analogue. The effect of A501 on cell viability was detected by MTT assay, the ...
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Population-based Cervical Cancer Screening Using Highrisk HPV DNA Test and Liquid-based Cytology in Northern Thailand
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Northern Thailand is a region with a high cervical cancer incidence. Combined high-risk HPV (hrHPV) DNA testing and cytology (co-testing) has increasingly gained acceptance for cervical cancer screening. ...
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Establishment and Partial Characterization of an Epirubicin-Resistant Gastric Cancer Cell Line with Upregulated ABCB1
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Multidrug resistance (MDR) is a major impediment to successful chemotherapy of gastric cancer. Our aim was to establish an epirubicin-resistant cell subline (AGS/EPI) and to elucidate the mechanisms involved in acquired ...
