Volume 14, Issue 9
مرور بر اساس
ارسال های اخیر
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View Point: How to Make Women Familiar with their Breasts?
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)There is a consensus among researchers about the fact that women should be familiar with their breasts butthere is a lot of argument as to how to make them aware of what is normal for them. For over decades breast ...
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miR-10b Promotes Migration and Invasion in Nasopharyngeal Carcinoma Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)MicroRNA-10b (miR-10b) has been reported to play an important role in some types of cancer, but the effectsand possible mechanisms of action of miR-10b in the metastasis of nasopharyngeal carcinoma cells (NPC) havenot been ...
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The Blood Neutrophil-to-lymphocyte Ratio Predicts Survival in Patients with Advanced Hepatocellular Carcinoma Receiving Sorafenib
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background and Aim: Increasing evidence correlates the presence of systemic inflammation with poorsurvival in patients with hepatocellular carcinoma (HCC). The aim of this study was to investigate theprognostic significance ...
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Anti-proliferation Effects of Interferon-gamma on Gastric Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)IFN-γ plays an indirect anti-cancer role through the immune system but may have direct negative effects oncancer cells. It regulates the viability of gastric cancer cells, so we examined whether it affects their proliferationand ...
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Alu Hypomethylation in Smoke-Exposed Epithelia and Oral Squamous Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: Alu elements are one of the most common repetitive sequences that now constitute more than10% of the human genome and potential targets for epigenetic alterations. Correspondingly, methylation of ...
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Prognostic Significance of Basic Laboratory Methods in Non-Small-Cell-Lung Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: In our study, the LDH, albumin, hemoglobin, neutrophile, thrombocyte, lymphocyte countsand prognostic significance of neutrophile-lymphocyte and thrombocyte-lymphocyte ratios in NSCLC derivedfrom these ...
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Relationship Between the Body Mass Index and Abnormal Pap Smears
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)This cross-sectional analytic study aimed to investigate any relationship between the body mass index (BMI)and an abnormal Pap smear. The subjects were 7,720 women aged 30-69 years who lived in Khon Kaen Province,Thailand, ...
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DNA Repair Capacity in Peripheral Blood Lymphocytes Predicts Efficacy of Platinum-based Chemotherapy in Patients with Gastric Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Objective: To investigate the correlation between ERCC1 expression levels in tumor tissue and peripheralblood lymphocytes (PBL) from patients with gastric cancer and assess the relationship between PBL DNA ...
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Acidic Pelvic Drainage as a Predictive Factor For Anastomotic Leakage after Surgery for Patients with Rectal Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Purpose: To demonstrate the value of sequential determinations of pelvic drainage in the identification ofincreased risk of anastomotic leakage (AL) after anterior resection for rectal cancer with a double staplingtechnique. ...
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Impact of Co-transfection with Livin and Survivin shRNA Expression Vectors on Biological Behavior of HepG2 Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Objective: To construct short hairpin RNA (shRNA) eukaryotic expression vectors targeting Livin andSurvivin genes, and to explore the impact of co-transfection of Livin and Survivin shRNA expression vectors ...
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Combined Germline Variations of Thrombophilic Genes Promote Genesis of Lung Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: A large variety of familiar and non-familiar lung carcinomas (LC) are caused by long termexposure to chemical carcinogens that are present in tobacco smoke. We aimed to investigate the prevalenceof 5 ...
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Menadione (Vitamin K3) Induces Apoptosis of Human Oral Cancer Cells and Reduces their Metastatic Potential by Modulating the Expression of Epithelial to Mesenchymal Transition Markers and Inhibiting Migration
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Oral cancer is one of the most commonly occurring cancers worldwide, decreasing the patient’s survival ratedue to tumor recurrence and metastasis. Menadione (Vitamin K3) is known to exhibit cytotoxicity in variouscancer ...
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Sonographic Pattern Recognition of Endometriomas Mimicking Ovarian Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: To assess the accuracy of ultrasound in differentiating endometrioma from ovarian cancer andto describe pattern recognition for atypical endometriomas mimicking ovarian cancers. Materials and ...
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P53 Arg72Pro and MDM2 SNP309 Polymorphisms Cooperate to Increase Lung Adenocarcinoma Risk in Chinese Female Non-smokers: A Case Control Study
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: Cell cycle deregulation is a major component of carcinogenesis. The p53 tumor suppressorgene plays an important role in regulating cell cycle arrest, and mouse double minute 2 (MDM2) is a keyregulator ...
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CXCL12-CXCR4 Promotes Proliferation and Invasion of Pancreatic Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Objective: CXCL12 exerts a wide variety of chemotactic effects on cells. Evidence indicates that CXCL12,in conjunction with its receptor, CXCR4, promotes invasion and metastasis of tumor cells. Our objective ...
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Lentivirus Mediated GOLPH3 shRNA Inhibits Growth and Metastasis of Esophageal Squamous Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Aim: To investigate the role of Golgi phosphoprotein 3 (GOLPH3) in tumour growth and metastasis ofesophageal squamous cancer. Methods: A lentiviral shRNA-vector was utilized to stably knockdown GOLPH3in Eca-109 ...
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Antioxidant Effects of Gamma-oryzanol on Human Prostate Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: To assess the antioxidant effects of gamma-oryzanol on human prostate cancer cells. Materialsand Methods: Cytotoxic activity of gamma-oryzanol on human DU145 and PC3 prostate cancer cells ...
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Anti-metastatic Potential of Ethanol Extract of Saussurea involucrata against Hepatic Cancer in vitro
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)The rates of morbidity and mortality of hepatocellular carcinoma (HCC) have not lessened because ofdifficulty in treating tumor metastasis. Mongolian Saussurea involucrata (SIE) possesses various anticanceractivities, ...
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Association Between the c.3751G>A Genetic Variant of MDR1 and Hepatocellular Carcinoma Risk in a Chinese Han Population
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)The objective of this study was to evaluate the influence of a genetic variant in the multidrug resistance 1 gene(MDR1) on hepatocellular carcinoma (HCC) risk. This case-control study was conducted in a Chinese populationof ...
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Prognostic Impact of Histology in Patients with Cervical Squamous Cell Carcinoma, Adenocarcinoma and Small Cell Neuroendocrine Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2013-09-01)Background: Clarifying the prognostic impact of histological type is an essential issue that may influence thetreatment and follow-up planning of newly diagnosed cervical cancer cases. This study aimed to evaluate ...
