Background: To investigate the inhibitory effect and the underlying mechanism of triptolide on culturedhuman endometrial carcinoma HEC-1B cells and corresponding xenograft. Materials and Methods: For in ...

Background: Missense and frame-shift mutations within the dimer forming domain of the caspase 8 genehave been identified in several cancers. However, the genetic status of this region in precancerous lesions, likeoral ...

Background: To investigate the effects of ASMase mediated endothelial cell apoptosis in multiplehypofractionated irradiations in CT26 tumor bearing mice. Materials and Methods: Thirty-five CT26 tumorbearing ...

Alterations in mitochondrial DNA (mtDNA) have been studied in various cancers. However, the clinical valueof mtDNA copy number (mtCN) alterations in gastric cancer (GC) is poorly understood. In the present study,we ...

Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat tothe human population worldwide. Since cancer is a progressive disorder, timely diagnosis would be helpful ...

Purpose: To evaluate the correlation between cosmetic outcome (CO), body image, and quality of life in postbreast-conserving therapy (BCT) women. Materials and Methods: This cross-sectional study concerned ...

Background: Colorectal cancer (CRC) is becoming one of the most complicated challenges of human health,particularly in developing countries like Iran. In this paper, we try to characterize CRC cases diagnosed

Objective: To investigate the influence of offspring-related characteristics on the prevalence of depressivedisorders among cancer patients and those who survived cancer for at least 45 years. Materials and ...

Background: Opisthorchis viverrini (OV) infection is the main risk factor for cholangiocarcinoma and is oftenfound in Northeastern Thailand. The prevalence of OV infection and the incidence of cholangiocarcinoma ...

In this review we summarize the results of studies employing high-throughput methods of profiling ofHPV-associated cervical intraepithelial neoplasia (CIN) and squamous cell cervical cancers at key intracellularregulatory ...

Background: To determine the potential value of serum tumor markers in predicting pCR (pathologicalcomplete response) during neoadjuvant chemotherapy. Materials and Methods: We retrospectively monitoredthe ...

The present investigation was designed to assess the anticancer activity of six different leaf extracts (ethylacetate, methanol, chloroform, petroleum ether, n-butanol, and water soluble) of Abelia triflora on A-549 humanlung ...

Background: Endometrial carcinoma is the most common malignant tumor of the female genital tract andthe fourth most common cancer in Iranian women after breast, colorectal and lung cancers. Various geneticalterations ...

Background: Folylpolyglutamate synthetase (FPGS), an important enzyme in the folate metabolic pathway,plays a central role in intracellular accumulation of folate and antifolate in several mammalian cell types. Loss ...

Background: Though a large proportion of cancer survivors are assumed to be commonly affected by sleepdisturbance, few studies have focused on short sleep problems and its correlates among Korean cancer survivors.The ...

Background: This study aimed to determine the utility and a cut-off level of serum squamous cell carcinomaantigen (SCC-Ag) to predict lymph node metastasis in locally advanced cervical cancer cases. We also ...

Echinodermata use saponins in chemical defense against pathogens and predators. The molecular mechanismsof antimetastatic effects of brittle star saponins are still unknown. The present study examined antioxidantcapacity ...

The aim of this study was to assess the diagnostic value of RASSF1A methylation in renal cell carcinoma.Systematically search were performed using the Pubmed, ProQest and Web of Science for all articles on theassociation ...

Background: In recent decades, the prognosis for childhood leukemia has improved, especially for acutelymphoblastic leukemia (ALL). In Thailand, though, the survival rate for ALL is unimpressive. In 2006, standardnational ...

Background: The survival of patients with hypopharyngeal cancer is low amongst head and neck cancer cases.The incidence rates of hypopharyngeal cancers in our population are amongst the highest in the world and ...