Background: Gastric cancer is the second leading cause of cancer-related death in Asia, and the majoritytype is gastric adenocarcinoma (GAC). Most GAC patients die of recurrence and metastasis. Cancer stem cells(CSCs) ...

Background: Colorectal cancer (CRC is increasingly becoming a major cause of cancer morbidity andmortality in Jordan. However the population’s level of awareness about CRC, CRC screening test preferencesand willingness ...

Background: Public awareness/knowledge on oral and pharyngeal cancer (OPC), potentially malignantdisorders (PMODs) and their risk factors is crucial for prevention and early detection of OPC and PMODs.Yet, there are ...

Breast cancer is a menacing cancer, primarily affecting women. Continuous research is going on for detectingbreast cancer in the early stage as the possibility of cure in early stages is bright. There are two main objectivesof ...

Background: Breast cancer is the most common cause of deaths of cancer in women. Nowadays, followingcompletion of imaging methods, mainly fine needle aspiration biopsy (FNAB) and core biopsy methods havebeen used ...

Purpose: Blood hemoglobin levels are known to influence response to radiotherapy. This retrospectiveanalysis compared the effect of hemoglobin levels upon response to radiation among patients treated withradiation alone ...

Background: Prognostic biomarkers in breast cancer are routinely investigated in the primary tumors to guidefurther management. However, it is proposed that the expression may change during the disease progression,and ...

Hepatocellular carcinoma (HCC) is a primary liver cancer with high global incidence and mortality rates.Current candidate drugs to treat HCC remain lacking and those in use possess undesirable side effects. In thisinvestigation, ...

Background: A protective effect of resistant starch (RS) containing foods on carcinogenesis has been shownfrom several lines of experimental evidence for gastrointestinal cancers. Therefore, we aimed to investigatethe ...

Background: To investigate the change of frequency and immuno-inhibitory function of myeloid-derivedsuppressor cells (MDSCs) after treatment of cisplatin (DDP) in A375 human melanoma model. Materials andMethods: ...

Background: Hydronephrosis is frequently encountered in advanced stage cervical cancers, and may beassociated with mortality. In the present study, we aimed to demonstrate the effect of hydronephrosis on survivalin ...

Background: Nasopharyngeal cancer is a disease with distinct ethnic and geographical distribution. The aimof this review was to describe the epidemiological characteristics of nasopharyngeal cancer in Iran from ...

Gastric cancer (GC) is one of the most common malignancies in the world. It is the first cause of cancerdeaths in both sexes In Iranian population. Circulating insulin-like growth factor-one (IGF-1) levels have beenassociated ...

Objectives: To investigate the expression of vimentin and Ki-67 proteins in cervical squamous cell carcinoma(CSCC) and their relationships with patient clinicopathological features. Materials and Meth ...

Background: Tight junctions (TJs) organise paracellular permeability and they have an important role inepithelial and endothelial cell polarity and permanence of barrier function. It has been demonstrated that ...

Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capitalcity of Turkey, from a histopathological point of view. Materials and Methods: Medical records ...

Background: Oral carcinoma (OC) remains as one of the most difficult malignancies to cure. Hesa-A is anIranian herbal-marine compound that has shown promising anti-tumor properties on various human cancercells, ...

Background: Levofloxacin is an effective medication for second line Helicobacter pylori (H. pylori) eradication.However, limited studies have approved its use as an effective antibiotic in first line therapy. ...

Background: Exposure to cigarette may affect human health and increase risk of a wide range of diseasesincluding pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), asthma, lung fibrosis andlung ...

The Bhopal gas tragedy involving methyl isocyanate (MIC) is one of the most horrific industrial accidentsin recent decades. We investigated the genotoxic effects of MIC in long-term survivors and their offspring bornafter ...