Volume 14, Issue 6
مرور بر اساس
ارسال های اخیر
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Predominant Genotypes and Alleles of Two Functional Polymorphisms in the Manganese Superoxide Dismutase Gene are Not Associated with Thai Cervical or Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Defects of manganese superoxide dismutase (MnSOD) have long been implicated in generationof oxidative stress and risk susceptibility to various cancers. Two functional polymorphisms within the MnSODgene, ...
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Expression and Significance of ER, PR, VEGF, CA15-3, CA125 and CEA in Judging the Prognosis of Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Objective: To explore the expression and significance of estrogen receptor (ER), progestrone receptor(PR), vascular endothelial growth factor (VEGF), CA15-3, CA125 and carcinoma embryonic antigen (CEA)expression ...
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Antiproliferative Activity of Lavatera cashmeriana- Protease Inhibitors towards Human Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Proteases play a regulatory role in a variety of pathologies including cancer, pancreatitis,thromboembolic disorders, viral infections and many others. One of the possible strategies to combat thesepathologies ...
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Serum Gastrin and the Pepsinogen I/II Ratio as Markers for Diagnosis of Premalignant Gastric Lesions
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Iran is a country with very high incidences of stomach cancer, especially in Northern parts.Here we assessed prognostic value of serum screening biomarkers among people >50 years old for early detectionof ...
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Prognostic Value of T Cell Immunoglobulin Mucin-3 in Prostate Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Optimal treatment for prostate cancer remains a challenge worldwide. Recently, T cellimmunoglobulin mucin-3 (TIM-3) has been implicated in tumor biology but its contribution prostate cancerremains unclear. ...
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Impact of Postoperative Chemoradiotherapy and Chemoradiotherapy Alone for Esophageal Cancer in North-West Iran
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: To investigate the role of surgical treatment for locally advanced esophageal cancer, we comparedthe outcomes of chemoradiotheroy alone (CRT) to postoperative chemoradiotherapy (S/CRT), using, ...
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CYP1A1 (Ile462Val), CYP1B1 (Ala119Ser and Val432Leu), GSTM1 (null), and GSTT1 (null) Polymorphisms and Bladder Cancer Risk in a Turkish Population
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)We aimed to investigate bladder cancer risk with reference to polymorphic variants of cytochrome p450 (CYP)1A1, CYP1B1, glutathione S-transferase (GST) M1, and GSTT1 genes in a case control study. Polymorphismswere examined ...
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Expression and Significance of TSGF, CEA and AFP in Patients Before and after Radical Surgery for Colon Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Objective: To explore the expression and significance of tumor specific growth factor (TSGF), carcinoembryonicantigen (CEA) and alpha fetoprotein (AFP) in cancer tissue and serum of patients with colon cancer. ...
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Secondline Chemotherapy Versus Best Supportive Care in Patient with Malignant Pleural Mesothelioma: A Retrospective Study
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Introduction: Mesothelioma is a rare neoplasm arising from mesothelial surfaces with the malignant pleuralmesothelioma (MPM) as the most common form. Secondline chemotherapy in MPM is still controversial andin ...
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Risk Effects of GST Gene Polymorphisms in Patients with Acute Myeloid Leukemia: A Prospective Study
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Glutathione S-transferase (GST) enzyme levels are associated with risk of many cancers, including hematologictumours. We here aimed to investigate the relationships between GSTM1, GSTT1 and GSTP1 polymorphisms andthe risk ...
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Circulating Lymphocytes as Predictors of Sensitivity to Preoperative Chemoradiotherapy in Rectal Cancer Cases
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Objective: The objective of this study was to identify clinical predictive factors for tumor response afterneoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC). Methods: All ...
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Integration Sites and Genotype Distributions of Human Papillomavirus in Cervical Intraepithelial Neoplasia
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Objectives: To analyse HPV integration prevalence and genotype distributions in cervical intraepithelialneoplasia (CIN) in east part of China, furthermore to assess preferential sites for common HPV integrations ...
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Potential Therapeutic Efficacy of Curcumin in Liver Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Purpose: Liver cancer, one of the most common cancers in China, is reported to feature relatively highmorbidity and mortality. Curcumin (Cum) is considered as a drug possessing anti-angiogenic, anti-inflammationand ...
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S100A14 Promotes the Growth and Metastasis of Hepatocellular Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: S100A14 has recently been implicated in the progress of several types of cancers. This studyaimed to investigate the clinical significance and possible mechanisms of action of S100A14 in the invasion ...
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Serum Tumor Markers, Hypoxia-Inducible factor-1α HIF-1α and Vascular Endothelial Growth Factor, in Patients with Nonsmall Cell Lung Cancer Before and after Intervention
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Objective: To explore changes in the serum tumor makers, hypoxia-inducible factor-1α (HIF-1α) and vascularendothelial growth factor (VEGF) level and their relations in patients with non-small cell lung cancer ...
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Age Distribution of Breast Cancer from a Thailand Population-Based Cancer Registry
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Breast cancer is a common cancer worldwide. With the establishment of Thailand’s populationbasedcancer registry and availability of complete data from 2002-2011, it is of interest to investigate ...
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Association of XRCC1 Gene Polymorphisms with Breast Cancer Susceptibility in Saudi Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: X-ray repair cross-complementing group 1 (XRCC1) plays a key role in the base excision repairpathway, as a scaffold protein that brings together proteins of the DNA repair complex. XRCC1 is reported tobe ...
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Pitfalls in Reimbursement Decisions for Oncology Drugs in South Korea: Need for Addressing the Ethical Dimensions in Technology Assessment
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)This study aimed to discover to what extent ethical issues are considered in the reimbursement decision processbased on health technology assessment (HTA) in Korea, especially for oncology medications. Public summarydocuments ...
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Down-regulation of Protease-activated Receptor 4 in Lung Adenocarcinoma is Associated with a More Aggressive Phenotype
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)The role of protease-activated receptors (PARs) in lung tumors is controversial. Although PAR4 ispreferentially expressed in human lung tissues, its possible significance in lung cancer has not been defined. Thestudies ...
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Sociodemographic Predictors of Recall and Recognition of Colorectal Cancer Symptoms and Anticipated Delay in Help- Seeking in a Multiethnic Asian Population
(West Asia Organization for Cancer Prevention (WAOCP), 2013-06-01)Background: Colorectal cancer is the second most common cancer in Malaysia. The prognosis of the diseaseis excellent if detected at an early stage, but the majority of Malaysian patients present at late stages. We ...
