Background: Cancer metastasis depends on cell motility which is driven by cycles of actin polymerizationand depolymerization. Reactive oxygen species (ROS) and metabolic oxidative stress have long been associatedwith ...

Pim kinase-3(Pim-3), a member of serine/threonine protein kinases, has been implicated in multiple humancancers and involved in Myc-induced tumorigenesis. However, little is known regarding its expression andbiological ...

Background: Gastric cancer (GC) is one the common lethal cancers in Iran. Detection of GC in the early stageswould assesses to improve the survival of patients. In this study, we attempt to evaluate the accuracy of ...

Background: Methylenetetrahydrofolate reductase (MTHFR) is involved in amino acid synthesis and DNAfunction. Two common polymorphisms are reported, C677T and A1298C, that are implicated in a number ofhuman diseases, ...

Geographic information system (GIS) technology has useful applications for epidemiology, enabling thedetection of spatial patterns of disease dispersion and locating geographic areas at increased risk. In this study,we ...

Objective: To explore the application of joint detection of serum AFP, CA19-9, CA125 and CEA in identificationand diagnosis of cholangiocarcinoma (CC). Materials and Methods: The levels of serum ...

The main objective of this paper was to assess the influence of educational level on the survival of uterinecervix cancer patients in our population. A total of 224 patients were registered in our registry, of which 178 ...

Background: Non-synonymous polymorphisms in XRCC1 hase been shown to reduce effectiveness of DNArepair and be associated with risk of certain cancers. In this study we aimed to clarify any association betweenXRCC1 ...

Objectives: To investigate the effects of betaine on HeLa cell growth and apoptosis and molecular mechanisms.Materials and Methods: Concentrations of 0.1, 1.0, 5.0, 20.0, 100.0 mg/ml of betaine were ...

The aim of the present study was to evaluate the relative contribution of CYP1A2 isoforms (-3860 G/A,-2467T/delT and -163C/A) in control subjects and breast cancer patients to the metabolism of caffeine in humanliver. ...

Background: The principal aim of health service providers in the field of breast cancer is to detect andtreat lesions at an appropriate time. Therefore, identification of barriers to screening can be very helpful. ...

The purpose of this study is to describe the relationship between caregiver burden and perceived social supportamong caregivers of patients with cancer. The research was conducted in a university hospital in İzmir, ...

Background: This study was designed to investigate the value of CEA and CA199 in predicting the treatmentresponse to palliative chemotherapy for advanced gastric cancer. Materials and Methods: We studied ...

Background: Colorectal cancer (CRC) is the most common gastrointestinal cancer and the incidence isincreasing. CRC is more common with increasing age, but a proportion occurs in young adults, termed youngCRC. This ...

In spite of limited data regarding the safety or effectiveness of electronic cigarette introduced into themarket as a healthier alternative to tobacco smoking, its popularity has increased enormously. E-cigarettes ...

Objective: To explore the association of serum tumor abnormal protein (TAP) with other serologicalbiomarkers e.g. carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), carbohydrate antigen19-9 ...

Purpose: To retrospective assess the potential predictors for relapse and create an effective clinical mode forsurveillance after orchidectomy in clinical stage I non-seminomatous germ cell testicular tumors (CSI-NSGCTs).Materials ...

Radiotherapy has an important role in the treatment of prostate cancer. Three-dimensional conformalradiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT) and volumetric modulated arctherapy (VMAT) techniques ...

Background: Breast cancer is a common cancer affecting women in Malaysia and the use of complementary/alternative medicine (CAM) has been associated with delays in getting treatment. The aim of the study was toexplore ...

Background: Chronic hepatitis B virus (HBV) infection related hepatocellular carcinoma (HCC) is a majorhealth problem in the Asia-Pacific region including Thailand. Several factors have been proposed as contributingto ...