Nucleolin (C23) is an important anti-apoptotic protein that is ubiquitously expressed in exponentially growingeukaryotic cells. In order to understand the impact of C23 in radiation therapy, we attempted to investigate ...

Objective: To explore the application of joint detection of serum AFP, CA19-9, CA125 and CEA in identificationand diagnosis of cholangiocarcinoma (CC). Materials and Methods: The levels of serum ...

Objective: To explore the sensitivity of gastric cancer cells to chemotherapy drugs in elderly patients andits correlation with cyclooxygenase-2 (COX-2) expression in cancer tissue. Materials and Methods: ...

Background: To explore the expression of TS, RRM, ERCC1, TUBB3 and STMN1 genes in the tissues ofpatients with non-small cell lung cancer (NSCLC) and its significance in guiding the postoperative adjuvantchemotherapy. ...

Background: Glucose regulated protein 78 (GRP78) is a type of molecular chaperone. It is a possible candidateprotein that contributes to development of drug resistance. We first examined the involvement of GRP78 ...

Background: Non-synonymous polymorphisms in XRCC1 hase been shown to reduce effectiveness of DNArepair and be associated with risk of certain cancers. In this study we aimed to clarify any association betweenXRCC1 ...

Purpose: To examine the effectiveness of mitomycin-C and chemo-hyperthermia in combination for patientswith high-risk non-muscle-invasive bladder cancer. Materials and Methods: Between November 2011-September2013, ...

Background: Previous studies have suggested that Morinda citrifolia (Noni) has potential to reduce cancerrisk. Objective: The purpose of this study was to investigate the effect of Noni, cisplatin, and ...

The aim of the present study was to evaluate the relative contribution of CYP1A2 isoforms (-3860 G/A,-2467T/delT and -163C/A) in control subjects and breast cancer patients to the metabolism of caffeine in humanliver. ...

Purpose: To retrospective assess the potential predictors for relapse and create an effective clinical mode forsurveillance after orchidectomy in clinical stage I non-seminomatous germ cell testicular tumors (CSI-NSGCTs).Materials ...

Background: This study was designed to investigate the value of CEA and CA199 in predicting the treatmentresponse to palliative chemotherapy for advanced gastric cancer. Materials and Methods: We studied ...

Background: Chronic hepatitis B virus (HBV) infection related hepatocellular carcinoma (HCC) is a majorhealth problem in the Asia-Pacific region including Thailand. Several factors have been proposed as contributingto ...

Background: Cancer metastasis depends on cell motility which is driven by cycles of actin polymerizationand depolymerization. Reactive oxygen species (ROS) and metabolic oxidative stress have long been associatedwith ...

Background: Testicular tumors constitute a rare type of cancer affecting adolescents and young adultswith recent reports confirming an increase in incidence worldwide. The purpose of this study was to estimatethe ...

Background: Liposarcoma of the spermatic cord is rare and frequently misdiagnosed. The standardtherapeutic approach has been radical inguinal orchiectomy with wide local resection of surrounding softtissues. The ...

Background: Sirtuin7 (SIRT7) is a type of nicotinamide adenine dinucleotide oxidized form (NAD+)-dependentdeacetylase and the least understood member of the sirtuins family; it is implicated in various processes, ...

Background: Ras genes are thought to play an important role in human cancer since they have been foundto be activated frequently in several types of tumors including breast cancer, where the overall incidence ofK-RAS ...

The papillary patterned lesion of thyroid may be challenging with many diagnostic pitfalls. Tumor stromaplays an important part in the determination of the tumor phenotype. CD34 is thought to be involved in themodulation ...

Objective: To explore the immune reconstitution of CD4+T cells after allogeneic hematopoietic stem celltransplantation (Allo-HSCT) and its relationship with invasive fungal infection (IFI) in patients with ...

Background: Breast cancer is a common cancer affecting women in Malaysia and the use of complementary/alternative medicine (CAM) has been associated with delays in getting treatment. The aim of the study was toexplore ...