Background: Recent studies have shown that 3-deazaneplanocin A (DZNep), a well-known histonemethyltransferase inhibitor, disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, whileinhibiting proliferation ...

Associations of P16, MGMT, hMLH1 and hMLH2 with gastric cancer and their relation with MTHFR statusin gastric patients who were confirmed with pathological diagnosis were assessed. Aberrant DNA methylationof P16, MGMT, ...

Background: Faced with highly prevalent and recalcitrant cancer-related fatigue (CRF), together with theabsence of any official guidelines on management, numerous groups have been striving to seek and test ...

Objectives: This study was conducted to determine the relationship between lifestyle behavior and qualityof life (QoL) among cancer survivors in Korea. Methods: Data for a total of 471 (173 men, 298 ...

Goniothalamin is an active compound extracted from Goniothalamus griffithii, a local plant found innorthern Thailand. Goniothalamin inhibits cancer cell growth but is also toxic to normal cells. The aims ofthis study were ...

Cervical cancer is a commonly-encountered malignant tumor in women. Cervical screening is particularlyimportant due to early symptoms being deficient in specificity. The main purpose of the study is to assess theapplication ...

Background: The aim of this systematic review was to investigate whether stem cells could be effectivelyapplied in targeted therapy of breast cancer. Material and Method: A systematic literature search ...

Background: The ABO blood groups and Rh factor may affect the risk of lung cancer. Materials and Methods:We analyzed 2,044 lung cancer patients with serologically confirmed ABO/Rh blood group. A group ...

Spleen tyrosine kinase (SYK) is a non-receptor type cytoplasmic protein and a known tumor suppressor genein breast cancer. Polymorphisms in SYK have been reported to be associated with cell invasion/cell moralityand an ...

Background: Susceptibility to lung cancer has been shown to be modulated by inheritance of polymorphicgenes encoding cytochrome P450 1A1 (CYP1A1) and glutathione S transferases (GSTM1 and GSTT1), which areinvolved ...

Photodynamic therapy (PDT) is a promising cancer treatment modality that uses dye-sensitized photooxidationof biologic matter in target tissue. This study explored effects of the photosensitizer BCPD-17 during PDT ...

Background: The burden due to cancers is an emerging public health concern especially in resource-limitedcountries like Nigeria. The WHO estimates that cancer kills more people than tuberculosis, HIV/AIDS andmalaria ...

This systematic review was conducted to assess the efficacy and safety of bisphosphonates for preventionand treatment of osteopenia or osteoporosis in men with non-metastatic prostate cancer receiving androgendeprivationtherapy. ...

Background: This study used National Health and Nutrition Examination Survey III to study the relationshipbetween blood lead concentration and all cause, all cancer and lung cancer mortality in adults. Patients ...

Background: Genetic aberrations of DNA repair enzymes are known to be common events associatedwith different cancer entities. The aim of the present study was to analyze genetic associations of rs1805404(Asp81Asp) ...

Background: Breast cancer is one of the most frequent diseases in women today. Little information exists onmodifiable lifestyle factors including effects of ginger supplements (as an anti-oxidant and anti-inflamma ...

Background: The efficacy of erlotinib is controversial in patients with unknown EGFR mutational status.The aim of this study was to identify the clinicopathological factors that are predictive of erlotinob ...

Background: Dilantin sodium (phenytoin) is an antiepileptic drug, which is routinely used to controlgeneralized tonic clonic seizure and partial seizure episodes. A few case reports of oral squamous cell carcinomasarising ...

Background: Health Related Quality of Life (HRQoL) is an important aspect in identifying cancer patients’perceptions of being diagnosed with cancer and the assessment of treatment outcomes. The present studyaimedto ...