Triple-negative breast cancers (TNBC), characterized by absence of the estrogen receptor (ER) andprogesterone receptor (PR) and lack of overexpression of human epidermal growth factor receptor 2 (HER2),have a poor prognosis. ...

Background: Human papillomavirus (HPV) integration within the E2 gene has been proposed as a critical eventin cervical carcinogenesis. This study concerned whether HPV16 status and E2 gene intactness are predictive ...

Background: Cancer imposes significant economic challenges for individuals, families, and society. Householdsof cancer patients often experience income loss due to change in job status and/or excessive medical ...

Background: Lung cancer (LC) is still the primary cause of cancer deaths worldwide, and late diagnosis is amajor obstacle to improving lung cancer outcomes. Recently, elevated preoperative or pretreatment neutrophilto ...

Background: Cervical cancer is the second most common cancer among females and also the most preventable.In the literature there is abundant evidence that awareness regarding cervical cancer and its prevention is ...

Ginsenoside Rg1 is one effective anticancer and antioxidant constituent of total saponins of Panax ginseng(TSPG), which has been shown to have various pharmacological effects. Our previous study demonstrated thatRg1 had ...

Background: To evaluate efficacy and side effects of glycididazole sodium (CMNa) combined withchemotherapy (cisplatin plus 5-FU/folic acid, PLF) and radiotherapy in treating patients with locally advancednasopharyngeal ...

In the present study, we studied the hypermethylation of the human riboflavin transporter 2 (hRFT2) gene andregulation of protein expression in biopsies from resected tissues from Uighur cervical squamous cell carcinoma(CSCC) ...

Involvement of a multidisciplinary team in cancer care may have added benefits over the existing system ofpatient management. A paradigm shift in the current patient management would allow more focus on nutritionalsupport, ...

Background: DNA repair pathways play a crucial role in maintaining the human genome. Previous studiesassociated DNA repair gene polymorphisms (XPD Lys751Gln, XRCC1 Arg280His and XRCC1 Arg399Gln)with nasopharyngeal ...

Background: When dealing with breast cancer, early detection is closely associated with determining andclosely monitoring high risk groups. The aim of this study was to determine the preventable risk factors thatare ...

The aim of this study is to evaluate clinicopathologic characteristics and the multi-disciplinary treatment resultsof metaplastic breast cancer (MBC) patients treated in a single institute. Seventeen female patients with ...

Azoxymethane (AOM) is a potent genotoxic carcinogen which specifically induces colon cancer. Hyperlipidemiaand diabetes have several influences on colon cancer development, with genetic and environmental exposureaspects. ...

Background: Isoflavones, which are included in soybeans, have been suggested to protect against prostatecancer. Equol, one of isoflavones, is an intestinally derived bacterial metabolite of daidzein. A newly ...

Background: Talin-1 is a cytoskeleton protein that participates in cell migration and plays a role in tumorformation, migration, and metastasis in different types of cancer. Chinese investigators have observed that ...

Background: Secreted frizzled-related protein (SFRP) genes, new tumor suppressor genes, are negativeregulators of the Wnt pathway whose alteration is associated with various tumors. In ovarian cancer, SFRPsgenes ...

Background: The aim of this study was to evaluate the prognosis of patients with stage IA-IIB cervicalcarcinoma and to investigate a possible correlation of histology with prognosis. Materials and Methods: ...

Background: Health-related quality of life (HRQL) is a fundamental outcome in oncology patients and qualityof life (QOL) assessment requires clinically relevant questionnaires. The purpose of this study was ...

Background: Several recent studies have explored associations between pre-mir-218 polymorphism(rs11134527) and cancer risk. However, published data are still inconclusive. To obtain a more precise estimationof the ...

Background: Little is known about the cancer screening prevalence and correlates in older adults fromdifferent racial backgrounds. In the context of heightened efforts for prevention and early diagnosis, we ...