Objective: Breast Cancer is the most invasive disease and fatal disease next to lung cancer in human. Early detectionof breast cancer is accomplished by X-ray mammography. Mammography is the most effective and efficient ...

Objective: Although Kazakhstan has made significant investments to improve health and life expectancy of itspopulation, high cancer rates persist, with breast cancer being the most prevalent type. Factors contributing ...

Purpose: Glioblastoma multiform (GBM) is the most aggressive glial neoplasm. Researchers have exploited thefact that GBMs are highly vascularized tumors. Anti-angiogenic strategies including those targeting VEGF ...

Objective: This method is to reduce the risk of imprecise diagnosis associated with poor-quality CT images, thispaper presents a new technique designed to enhance the quality of medical CT images. The main objective ...

Background: Human papillomavirus (HPV) infection is associated with cervical cancer; however, it iscontroversial whether it is involved in non-cervical genital cancers. Objective: This study aimed to evaluate

Background: Urological cancers (prostate cancer and bladder cancers) are the most common cancers in Westernpopulation and its rate is increasing in the Eastern World. Autophagy has appeared as a fundamental repair ...

Background: P-glycoprotein (P-gp), a membrane transporter encoded by the multidrug resistance-1 (MDR1) gene,influences pharmacokinetics and metabolism of anticancer drugs and contributes to multidrug resistance ...

Clear cell carcinomas are common finding in renal, ovarian and uterine carcinomas. However, clear cell lungcancer (CCLC), first described by Liebow and Castleman in 1963, is considered an extremely rare variant of ...

Dysregulation in the miRNA-21 expression has been previously observed in a number of malignancies and not onlyin the tumor cell itself but also in the body fluids of the cancer patients. The present study aimed to ...

Background: Several studies indicate that chemokines play important roles in colorectal mucosal immunity.The chemokine CXCL5 which is expressed by epithelial cells within colorectal mucosa is a promoter of cell ...

Background: Phytoestrogens are a group of natural compounds with estrogen-like activity and similar structureto estradiol that structurally mimic the mammalian estrogen 17-β estradiol (E2). They have a biphasic effect ...

Objectives: To determine and compare the serum lipid profiles and anthropometric parameters of newly diagnosedBC patients and healthy women. Methods: Serum total cholesterol (TC), high density lipoprotein cholesterol ...

Objective: Paclitaxel (PTX) is a chemotherapeutic agent used for treating breast cancer. The study aimed to preparePTX loaded dextran stearate (Dex-SA) and evaluate its efficacy against human breast cancer cell line ...

Cancers are complex diseases having several unique features, commonly described as ‘hallmarks of cancer'. Amongthem, altered signaling pathways are the common characteristic features that drive cancer progression; ...

This quasi-experimental research aimed to study the effect of health behavior modification program in relation toknowledge, self-efficacy, expectation, and practice for liver fluke prevention among the risk group ...

Objective: In the present study, we aimed to evaluate the effects an exergaming protocol for cancer patients whoundergo or have already undergone cancer treatment. We sought to evaluate changes in cancer-related ...

Prediction of tumor volume using the Cavalieri method may be helpful in management of therapy and evaluation oftreatment results. The aim of this study was to adapt the Cavalieri stereological method to magnetic ...

Background/objective: HCC is a multistep process starting from chronic hepatitis that progress through cirrhosisto HCC. MicroRNA expression level was found to be deregulated in HCC. To find out whether the expression ...

Objective: To investigate the regulatory role of fibronectin (FN) in the formation of multicellular aggregate (MCA)in ovarian cancer SKOV3 and OVCAR-3 cells and integrin expression. Methods: The dynamic formation of ...

Objective: Glioblastoma (GBM) is the most malignant and aggressive type of glioma, associated with a high rateof mortality. The transforming growth factor-β receptor II (TGFβ RII) is involved in glioma initiation and ...