Purpose: To evaluate acute toxicity in nasopharyngeal cancer (NPC) patients treated with intensity modulatedradiotherapy (IMRT)/volumetric modulated arc therapy (VMAT) with or without cisplatin-based chemotherapy.Materials ...

Nasopharyngeal carcinoma is an endemic disease within specific regions in the world. Radiotherapy is themain treatment. In recent decades, intensity-modulated radiation therapy has undergone a rapid evolution.Compared with ...

Background: Elevated serum alpha-fetoprotein (AFP) levels in adults are considered abnormal. This parameteris used mostly in the diagnosis and follow-up of hepatocellular carcinomas and yolk sac tumors. Among the ...

Gecko is a kind of traditional Chinese medicine with remarkable antineoplastic activity. However, undefinedmechanisms and ambiguity regarding active ingredients limit new drug development from gecko. This study wasconducted ...

Eighty six cases of invasive ductal breast carcinomas were utilized to investigate GSTP1 polymorphisms incertain immunohistochemistry (IHC) subtypes of breast cancer with respect to ER, PR and HER2 expression.The frequency ...

Background: Associations between the NQO1 C609T polymorphism and hepatocellular carcinoma (HCC)risk are a subject of debate. We therefore performed the present meta-analysis to evaluate links with HCCsusceptibility. ...

Much interest has been drawn to possible associations between vitamin D receptor (VDR) gene polymorphismsand colorectal cancer risk in conjunction with potentially protective effects of calcium and vitamin D. In a studyof ...

Background: Breast and cervical cancers are the most common types of cancer in women worldwide. Previousstudies in Asia have shown that related knowledge and awareness is low among female university students. Thegoal ...

Background: In India, cancer accounts for 7.3% of DALY’s, 14.3% of mortality with an age-standardizedincident rate of 92.4/100,000 in men and 97.4/100,000 in women and yet there are no nationwide screeningprograms. ...

There has been a strong, positive correlation between opisthorchiasis-associated cholangiocarcinoma andinfection with Helicobacter. Here a rodent model of human infection with Opisthorchis viverrini was utilized tofurther ...

Background: Lymphoma is one of the most common malignancies affecting the young Saudi population.This disease has diversified pathologies and clinical stages that necessitate well optimized clinical management.Regular ...

Intra-tumoral hypoxia is an environment that promotes tumor cell migration, angiogenesis and epithelialmesenchymaltransition that accounts for a major mechanism of metastasis. Chloroquine potentially offers anew therapeutic ...

The heterogeneous nature of lung cancer has become increasingly apparent since introduction of molecularclassification. In general, advanced lung cancer is an aggressive malignancy with a poor prognosis. Activatingalterations ...

Objective: To evaluate the efficacy and adverse effects of three dimensional conformal radiotherapy (3D-CRT)with tamoxifen in treating patients with postoperative malignant glioma. Patients and Methods: ...

Background: miRNAs are relatively recently discovered cancer biomarkers which have important implicationsfor cancer early diagnosis, treatment and estimation of prognosis. Here we focussed on expression of mir-196a-5pin ...

Background: We generated a mouse model of prostate cancer based on the adult-prostate-specific inactivationof phosphatase and tensin homolog (PTEN) using the Cre-loxP system. The potential of our mice as a useful ...

Purpose: To determine the diagnostic yield of primary circulating tumor cells in women with suspicion ofbreast cancer, detected as a result of an abnormal mammography. Materials and Methods: Consecutive ...

Background: Oesophageal squamous cell carcinoma (ESCC) is endemic in the Eastern Anatolian region ofTurkey. The present study was performed to identify risk factors for ESCC that specifically reflect the demographyand ...