Background: One of the main contributors in low survival rate in LMIC is the lack of availability of cancermedications for curative, supportive and palliative care. In many developing countries access to cytotoxic ...

Objective: Despite advanced treatment options available, drug resistance develops in breast cancer (BC) patientsrequiring novel effective drugs. Stylissa carteri, a marine sponge predominantly living in Indonesia ...

Introduction: Refusal and abandonment of treatment is often considered as an important reason for poor survival ofpediatric cancer patients in developing and underdeveloped countries. In this study we analyze the ...

Introduction: India fights massive cervical cancer burden. This article highlights an innovative feasible approachenabling tertiary hospitals to contribute to cancer prevention without compromising their primary ...

Background: H. pylori is a class I carcinogen and major cause of gastric cancer. Few previous studies reportedrelationship between H. pylori infection, CYP2C19 genotype and functional dyspepsia (FD) subtype. The aim ...

Objective: Women with breast cancer experience functional limitations at the time of diagnosis and after the initialtreatment of cancer. Such limitations interfere with participation in self-care, work affairs, and ...

Objective: To develop and validate a simplified multi-parameter risk-based scoring system for preoperative diagnosisof early stage epithelial ovarian cancer. Methods: All women presented with adnexal mass and were ...

Background: In Brazil, little is known regarding the underlying causes of differences among populations regardingsocio-economic variables that affect women's cervical cancer screening behavior. The present study ...

Background: To evaluate the utility of the pharmacokinetic modeling derived from dynamic contrast-enhancedmagnetic resonance imaging (DCE-MRI) in differentiating benign from malignant adnexal masses. Methods: A total ...

Background: DNA demethylating agents and histone deacetylase inhibitors can affect reactivation of geneexpression and apoptosis induction by DNA acetylation and demethylation. The aim of the present study was to ...

Background and aim: Cigarettes, hookah, and tobacco are the most important etiologic factors for oral cancersand dysplastic lesions. This study was undertaken to determine the correlation between hookah use and the ...

Objective: UroVysion (Abbott Molecular, Inc., Illinois, USA) is based on multicolor fluorescence in situ hybridization(FISH). It has been used successfully in the USA following its Food and Drug Administration approval ...

Objective: To determine the factors associated with the increased risk of developing high-grade squamousintraepithelial lesions (HSIL) of the uterine cervix in women younger than 30 years compared with those aged ≥ ...

Abnormalities in the cervix, when identified early by Pap smear, can be treated in the early stages or in the precursorstages of the neoplasia, which may increase the chances of regression of the lesion. The aim to ...

Objective: to detect the HPV types distribution both in general female population and in women with first diagnosedcervical cancer, including viral load in both groups. Methods: Qualitative detection and quantification ...

Breast cancer is the most frequent malignancy among women. It is a heterogeneous disease with different subtypesdefined by its hormone receptor. A hormone receptor is mainly concerned with the progression of the ...

Background: Thyroid ultrasound(US) is used as the first diagnostic tool to assess the management of disease butis operator dependent. There have been few reports evaluating interrater variability in US assessment. ...

Objectives: Vast number of studies show the relationship between aneuploidy and cancer. Ionizing radiation inaddition to induce all kinds of damages to the cells and structure of chromosomes, is also able to induce ...

Objective: Evaluation of the neoadjuvant chemotherapy response can be performed by comparing the breast cancerburden and pathobiology before and after treatment. This study was aimed to investigate the pattern of ...

Objective: Human epidermal growth factor receptor 2 (erbb2/HER2) overexpression, has now been implicatedin advanced gastric and gastroesophageal junction cancers. The study was conducted to determine the rate of ...