Human papillomavirus (HPV) is responsible for one of the most frequent sexually transmitted infections.The first phylogenetic analysis was based on a LCR region fragment. Nowadays, 4 variants are known: African(Af-1, Af-2), ...

This study was conducted to investigate the plasma phosphoproteome and differential plasma phosphoproteinsin cases of of Opisthorchis viverrini (OV)-related cholangiocarcinoma (CCA). Plasma phosphoproteomes fromCCA patients ...

The aim of this study was to evaluate the effects of grape juice on colon carcinogenesis induced by azoxymethane(AOM) and expression of NF-kB, iNOS and TNF- α. Methods: Forty male Wistar rats were divided into ...

Objective: Glypican-3 (GPC3) is reported to be an oncofetal protein that is a useful diagnostic immunomarkerfor hepatoblastoma. However, the results are not inclusive. This study systemically investigated the ...

Malignant tumors are often accompanied by increased risk of hematological abnormalities. However, fewstudies have reported any prognostic impact of preoperative thrombocytosis, leukocytosis and anemia in epitheliaovarian ...

Background: This study reviewed the published evidence as to how prostate cancer outcomes vary acrossgeographical remoteness and area level disadvantage. Materials and Methods: A review of the literature ...

Background: Cancer imposes a significant economic burden on individuals, families and society. The purposeof this study was to estimate the economic burden of cancer using the healthcare claims and cancer registry ...

PTEN (phosphatase and tensin homologue), as a tumor suppressor gene, plays a significant role in regulatingcell growth, proliferation, and apoptosis. Results from published studies for association between the PTEN IVS4I/D ...

Side population (SP) cells have stem cell-like properties with a capacity for self-renewal and are resistantto chemotherapy and radiotherapy. Therefore the presence of SP cells in human breast cancer probably hasprognostic ...

Background: Expression of matrix metalloproteinases (MMPs) is up-regulated in human cancers. The aimof present study was to investigate the role of MMP-9 C-1562T polymorphism and its interaction with MMP-2 C-735T ...

Background: Artemisia species are important medicinal plants throughout the world. The present in vitrostudy, using a sesquiterpene lactone-bearing fraction prepared from Artemisia khorassanica (SLAK), sought ...

Background: Locally advanced head and neck cancer is generally incurable and has a short survival rate. Thisstudy aimed to evaluate symptom relief, disease response, and acute toxicity after palliative hypo-fracti ...

Background: Psoriasis, a common cutaneous disorder characterized by inflammation and abnormalepidermal proliferation with a prevalence of 2-3% in the general population, may be linked to certain types ofcancer. ...

Breast cancer is the leading cause of morbidity and mortality globally but has an even more significant impactin developing countries. Pakistan has the highest prevalence among Asian countries. A general lack of publicawareness ...

Background: Anal intraepithelial lesions (AIL) are likely to represent a precursor for anal cancer. Womeninfected with human immunodeficiency virus (HIV) may be at higher risk of anal cancer but a screening programfor ...

Background: To compare prevalence of anxiety in ovarian cancer patients following primary treatment tothat of normal women and to examine predicting factor. Materials and Methods: In this cross-sectional ...

Background: Since the survival rate of breast cancer patients has improved, harmful effects of new treatmentmodalities on fertility of the young breast cancer patients has become a focus of attention. This study ...

Background: The clinical significance of bilateral breast cancer is unclear and its influence on prognosis iscontroversial. Materials and Methods: Between 2005 and 2009 we identified 110 cases of bilateral ...

Matrix metalloproteinase-2 (MMP2) is an endopeptidase, mainly responsible for degradation of extracellularmatrix components, which plays an important role in cancer disease. A single nucleotide polymorphism (SNP)at -1306 ...

Background: To explore the relationship between CXCR4, CD133 co-expression and clinicopathologicalfeatures as well as prognosis of patients with phase Ⅱ~Ⅲ colon cancer. Materials and Methods: ...