To investigate the potential role of the notch ligand delta-like ligand 4 (DLL4) in glioma angiogenesis, weexamined whether its expression correlates with that of vascular endothelial growth factor (VEGF) and hypoxiaindu ...

The Section of Histopathology, Aga Khan University is the largest center for histopathology in Pakistan and isthe major reporting and referral center for CNS neoplasms in the country. Over the years, a significant increasehas ...

Alcohol consumption is one of the risk factors for colorectal cancers and adenomas. Since alcohol dehydrogenaseis a key enzyme in alcohol metabolism, it may thus play a role in colorectal carcinogenesis. The present study ...

Background: Warning labels on tobacco products provide an effective way of communicating the consequencesof tobacco use. Research has shown that larger and colorful warnings placed on packaging are more effectivefor ...

Purpose: β-catenin, the chief oncogenic component of the canonical Wnt pathway, is known to be involvedin development of a variety of cancers, but its role in human osteosarcomas is not fully understood. Here weinvestigate ...

Aim: To investigate effects of green tea drinking and its temperature on esophageal cancer development.Methods: A 1:2 matched hospital-based case-control study including 150 cases and 300 controls was conducted ...

The aim of this study was to evaluate the prognostic impact of hemoglobin (Hb) levels before and throughoutthe course of platinum-based chemotherapy in patients with primary epithelial ovarian cancer (EOC). Medicalrecords ...

Background: Breast cancer is the most common malignancy in women. Early diagnosis allows efficienttreatment and increases survival, but the efficacy of breast self examination (BSE) is not sufficiently wellestablished. ...

Objective: To determine risk factors of high-grade cervical intraepithelial neoplasia (CIN 2-3) among womenwith atypical squamous cells of undetermined significance (ASC-US) Papanicolaou (Pap) smears. ...

This descriptive study was conducted to determine the validity and reliability in Turkey of the PediatricQuality of Life Inventory Cancer Module (PedsQL 3.0) for children aged 8-12 in the hematology-oncologypolyclinics of ...

In India the incidence of breast cancer is on the rise and it is rapidly becoming the number one cancer infemales, pushing cervical cancer to the second spot. The contribution of BRCA2 to the development of the sporadicform ...

Background: The concordance rate between immunohistochemical (IHC) and fluorescence in situ hybridization(FISH) results for HER2/neu according to clinical performance is controversial. The present prospective studywas ...

Objectives: There is growing evidence that oxidative stress (OS) has a causal relationship with cancerand a weak antioxidant defense can aggravate it further. We therefore, undertook this study to examine ...

One of the main aims of cancer chemopreventive studies is to identify ideal apoptotic inducers, especiallyexamples which can induce early apoptotic activity. The present investigation focused on chemopreventive effectsof ...

Cancer is the second leading cause of death in children and survivors require life time follow-up. There is agrowing recognition of the need to base cancer control policies on accurate, detailed and timely information ...

Aim: To describe health beliefs and breast self-examination (BSE) practice of Turkish female nursing andmidwifery students and extent of teaching the screening method to their mothers, sisters and relatives. Design:In this ...

Background: Thyroid cancer is the most common endocrine system malignancy in the world, being the 7thmost common cancer in females, 14th in males and 11th in both sexes in the Iranian population. The presentstudy ...

Introduction: The aim of this study was to survey the clinical and pathological features of breast cancer inthe Center of Tunisia. Design: Characteristics of all breast cancer cases diagnosed in the Pathology ...

Paclitaxel is one of the key chemotherapeutic drugs widely used to treat various types of cancer. Many cervicalcancer patients exhibit selectivity in response to thereapy, however, which is considered to be correlated ...