Volume 3, Issue 3
مرور بر اساس
ارسال های اخیر
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Normal Expression of cytotoxic T-lymphocyte-associated protein 4 (CTLA4) in LPS-responsive and beige-like anchor protein (LRBA) Patient
(Research Center For Immunodeficiencies, 2020-09-01)Bialelic LRBA mutations leads to an Immune dysregulation disorder which name is LRBA deficiency. A wide spectrum of clinical manifestation associated with recurrent infections, enteropathy, hypogammaglobulinemia, and ...
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Case Report: MALT1 Mutation in A Patient with Severe Combined Immunodeficiency
(Research Center For Immunodeficiencies, 2020-09-01)Severe combined immunodeficiency (SCID) is one of the most serious and life-threatening forms of primary immunodeficiency disorders (PID). SCID patients manifest a large clinically heterogeneous group of monogenic disorders ...
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Bronchiectasis in Patients with the Common Variable Immunodeficiency (CVID)
(Research Center For Immunodeficiencies, 2020-09-01)Background/objectives: the common variable immunodeficiency (CVID) is known as the most prevalent symptomatic primary immune deficiency (PID) diseases, which is characterized by lower antibody serum levels as well as several ...
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Activated PI3K-Delta Syndrome: Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management
(Research Center For Immunodeficiencies, 2020-09-01)Activated PI3 kinase delta syndrome (APDS) is a newly recognized primary immunodeficiency that was firstly discovered in 2013. APDS can result from gain-of-function mutations in PI3Kδ catalytic p110δ (PIK3CD known as APDS1) ...
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Comparison of the Familial and Sporadic Forms of Hyper IgM Syndrome in the Iranian Patients
(Research Center For Immunodeficiencies, 2020-09-01)Background/Objectives: Hyper IgM (HIGM) syndrome or immunoglobulin class-switch recombination deficiency (Ig-CSR) is a group of primary immunodeficiencies (PIDs) where B cells are unable to undergo the process of immunoglobulin ...
