Preparation of 1,5-diaryl-3-(arylamino)-1H-pyrrol- 2(5H)-one derivatives using 1-methylpiperidinium hydrogen sulfate as an efficient catalyst

Abstract

A highly efficient and environmentally friendly synthesis of various 1,5-diaryl-3-(arylamino)-1H-pyrrol-<br />2(5H)-ones catalyzed by 1-methylpiperidinium hydrogen sulfate via one-pot cyclo-condensation reaction of<br />aldehydes, amines and ethyl 2-oxopropanoate under ambient conditions has been explored. The present<br />methodology offers several advantages such as good yields, simple procedure, shorter reaction times and<br />milder conditions and the products were purified without resorting to chromatography.