Application of Sulfonic Acid Functionalized SBA-15 as a Nanoporous Acid Catalyst in Microwave Assisted Synthesis of 2-Aryl Benzoxazoles

Abstract

Sulfonic acid functionalized SBA-15 as a nanoporous acid catalyst was used in the synthesis of 2-Aryl benzoxazoles 4 by the condensation of 2-aminophenol 1 and benzoyl chlorides 2 under microwave irradiation in solvent free reaction conditions. The advantages of this methodology are good product yields (60-98%), being environmentally benign, short reaction times and easy work up.